Clinical Trials Logo
  1. Home
  2. Emergence Delirium
  3. NCT04058899

Dexmedetomidine Versus Nalbuphine in Prevention of Emergence Agitation Following Adenotonsillectomy in Pediatrics

Emergence Delirium Clinical Trial

Official title:
Dexmedetomidine Versus Nalbuphine in Prevention of Emergence Agitation Following Adenotonsillectomy in Pediatrics

Clinical Trial Summary

The aim of the present study is to compare the effect of IV infusion 0.5 µg/kg dexmedetomidine and IV 0.1 mg/kg nalbuphine in preschool children for prevention of emergence agitation after adenotonsillectomy under sevoflurane anesthesia.

Clinical Trial Description

Consent will be obtained from legal guardian of children,patients will be randomized according to computer randomization to one of two groups, dexmedetomidine group (DEX)group who will receive 0.5 µg/kg dexmedetomidine diluted in 50 ml of normal saline 0.9% to be given by IV infusion over 10 minutes after induction of anesthesia then 5ml of 0.9% normal saline IV ,nalbuphine group (NAL)group will receive IV infusion of 50 ml of 0,9%normal saline by IV infusion over 10 minutes then 0.1mg/kg nalbuphine diluted in 5ml of 0.9%normal saline IV after induction of anesthesia. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04058899
Study type Interventional
Source Ain Shams University
Contact
Status Active, not recruiting
Phase Phase 1/Phase 2
Start date March 5, 2019
Completion date September 2019
View Details
See also
  Status Clinical Trial Phase
Completed NCT03787849 - Epigenetics in PostOperative Pediatric Emergence Delirium N/A
Completed NCT03788564 - The Association of Cardiac Ion Channel Related Gene Polymorphism and Prolonged QTc Interval After Endotracheal Intubation
Recruiting NCT01221025 - Effect Study of Parecoxib to Treat Emergence Delirium and Postoperative Pain Phase 4
Not yet recruiting NCT06035757 - The Occurrence of Emergence Agitation in Pediatric Strabismus Surgery Phase 4
Not yet recruiting NCT04291820 - Impact of Anaesthesiology Management on Paediatric Emergence Delirium Incidence N/A
Completed NCT05124067 - Effect of Dexmedetomidine on Prevention of Postoperative Nausea and Vomiting in Children Phase 1
Recruiting NCT05091242 - The PREVENT AGITATION Trial II - Children ≤1 Year Phase 2/Phase 3
Completed NCT03330236 - EEG - Guided Anesthetic Care and Postoperative Delirium N/A
Completed NCT04531020 - Incidence of Emergence Delirium in the PACU
Completed NCT05105178 - Verbal Stimulation of Orientation on Emergence Agitation N/A
Completed NCT03285243 - Effect of Monochromatic Light on Incidence of Emergence Delirium in Children N/A
Recruiting NCT04621305 - Remimazolam Reduces Emergence Delirium in Preschool Children Undergoing Laparoscopic Surgery by Sevoflurane Anesthesia Phase 4
Completed NCT01096797 - Correlation Between Pain and Emergence Delirium After Adenotonsillectomy in Preschool Children Phase 4
Recruiting NCT03330613 - Emergence Delirium and Recovery Time in Children N/A
Recruiting NCT05872087 - Comparative Study Between Nebulised Dexmedetomidine and Nebulised Midazolam in Children Undergoing Lower Abdominal Surgeries Phase 1
Not yet recruiting NCT06387953 - Mitigation of Emergence Agitation Through Implementation of Masimo Bridge Therapy N/A
Not yet recruiting NCT05883280 - The Effect of Binaural Sound on the Occurrence of Emergence Delirium in Children Undergoing Strabismus Surgery N/A
Not yet recruiting NCT05821972 - Nebulized Dexmedetomidine Combined With Ketamine Versus Nebulized Dexmedetomidine for Cleft Palate Phase 4
Completed NCT03131375 - Dexmedetomidine Reduces Emergence Delirium in Children Undergoing Tonsillectomy With Propofol Anesthesia Phase 2/Phase 3
Completed NCT04292457 - Namsos Anaesthesia Children Outcome Study N/A