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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT04245241
Other study ID # EIT-HFNC
Secondary ID
Status Completed
Phase
First received
Last updated
Start date May 1, 2018
Est. completion date November 1, 2019

Study information

Verified date January 2020
Source Peking Union Medical College Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This study aimed to determine the effects of HFNC therapy on lung recruitment and lung strain change assessed by electrical impedance tomography (EIT)


Recruitment information / eligibility

Status Completed
Enrollment 24
Est. completion date November 1, 2019
Est. primary completion date July 1, 2019
Accepts healthy volunteers No
Gender All
Age group 18 Years to 85 Years
Eligibility - Inclusion Criteria:

- Patient who received a HENC therapy within 24 h after the extubation

Exclusion Criteria:

- Aged <18 years

- Pregnancy

- Body mass index (BMI) over 50 kg/m2

- ribcage malformation .any contraindication of using EIT monitoring (automatic implantable cardioverter defibrillator, chest skin injury, etc.).

Study Design


Intervention

Other:
High-flow nasal cannula (HFNC)
24 patients who receiving HFNC within 24 hours after extubation were prospectively enrolled in this study. EIT was used to monitor regional lung ventilation distributions at baseline (conventional oxygen therapy) and three flow rate levels of HFNC therapy (20, 40 and 60 L/min).

Locations

Country Name City State
China Department of Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing Beijing

Sponsors (1)

Lead Sponsor Collaborator
Peking Union Medical College Hospital

Country where clinical trial is conducted

China, 

Outcome

Type Measure Description Time frame Safety issue
Primary lung regional ventilation distribution lung regional ventilation distribution measured by EIT minute 80
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