Efficacy of Dexamethasone in Treatment of Meconium Aspiration Syndrome

Status Completed

Clinical Trial Summary

Objective: To determine efficacy of dexamethasone in treatment of meconium aspiration syndrome. Study design: Randomized control trial. Place and duration: Services hospital, Neonatal unit, Lahore. During time span of 1st January to 30th June 2021. Material and methods Total 100 neonates were randomly divided in two groups. Group A (n=50) was treated with dexamethasone (Cases) and Group B (n=50) served as control. Dexamethasone was given in dose of 0.2mg/kg, 12 hourly for 7 days after confirmation of diagnosis. Infants present in clinical trial were evaluated by ventilation duration (invasive and non-invasive), oxygen therapy and hospital stay.

Clinical Trial Description

Data was analyzed in statistical analysis SPSS version 23. Means and Standard deviation were calculated for duration of non-invasive and invasive ventilation, hospital stay and oxygen therapy. Independent sample T test was applied and value < 0.05 was taken as significant. Whereas frequency and percentages were taken for gender, gestation, mode of delivery and outcome of MAS and Chi-square test was applied, and p value < 0.05 was taken as significant. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05517499
Study type	Interventional
Source	Services Institute of Medical Sciences, Pakistan
Contact
Status	Completed
Phase	N/A
Start date	January 1, 2021
Completion date	June 30, 2021

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