Edema Clinical Trial
Official title:
Impact of Preemptive Intravenous Ibuprofen on Postoperative Edema and Trismus in the Third Molar Teeth
Verified date | May 2017 |
Source | Erzincan University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
this study was planned to investigate the antiinflammatory activity of preemptive intravenous ibuprofen on inflammatory complications such as edema and trismus after third molar tooth surgery
Status | Active, not recruiting |
Enrollment | 60 |
Est. completion date | November 15, 2017 |
Est. primary completion date | October 30, 2017 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 20 Years to 35 Years |
Eligibility |
Inclusion Criteria: - Elective 3. Molar tooth extraction - Patients between the ages of 20-35 - Patients who are symptomatic - 3. Molar tooth angular or horizontal settled patients Exclusion Criteria: - Patients who refuse to participate in the study - Patients under 20 years old, over 35 years old - Patients who are allergic to known non-steroidal anti-inflammatory drugs - Pregnant patients - Patients with severe hepatic insufficiency - Patients with severe renal insufficiency |
Country | Name | City | State |
---|---|---|---|
Turkey | Erzincan University | Erzincan |
Lead Sponsor | Collaborator |
---|---|
Erzincan University |
Turkey,
Agarwal S, Chattopadhyay S, Mandal M. Comparison of efficacy of aceclofenac and ibuprofen after surgical removal of impacted third molar. J. Evolution Med. Dent. Sci. 2017;6(21):1670-1677, DOI: 10.14260/Jemds/2017/368
Bouloux GF, Steed MB, Perciaccante VJ. Complications of third molar surgery. Oral Maxillofac Surg Clin North Am. 2007 Feb;19(1):117-28, vii. Review. — View Citation
Chukwuneke F, Onyejiaka N. Management of postoperative morbidity after third molar surgery: a review of the literature. Niger J Med. 2007 Apr-Jun;16(2):107-12. Review. — View Citation
Chukwuneke FN, Oji C, Saheeb DB. A comparative study of the effect of using a rubber drain on postoperative discomfort following lower third molar surgery. Int J Oral Maxillofac Surg. 2008 Apr;37(4):341-4. doi: 10.1016/j.ijom.2007.11.016. Epub 2008 Feb 12. — View Citation
Colorado-Bonnin M, Valmaseda-Castellón E, Berini-Aytés L, Gay-Escoda C. Quality of life following lower third molar removal. Int J Oral Maxillofac Surg. 2006 Apr;35(4):343-7. Epub 2005 Nov 8. — View Citation
Jain N, Maria A. Randomized double blind comparative study on the efficacy of Ibuprofen and aceclofenac in controlling post-operative sequelae after third molar surgery. J Maxillofac Oral Surg. 2011 Jun;10(2):118-22. doi: 10.1007/s12663-011-0198-9. Epub 2 — View Citation
Jerjes W, El-Maaytah M, Swinson B, Banu B, Upile T, D'Sa S, Al-Khawalde M, Chaib B, Hopper C. Experience versus complication rate in third molar surgery. Head Face Med. 2006 May 25;2:14. — View Citation
Markovic A, Todorovic Lj. Effectiveness of dexamethasone and low-power laser in minimizing oedema after third molar surgery: a clinical trial. Int J Oral Maxillofac Surg. 2007 Mar;36(3):226-9. Epub 2006 Dec 8. — View Citation
Sato FR, Asprino L, de Araújo DE, de Moraes M. Short-term outcome of postoperative patient recovery perception after surgical removal of third molars. J Oral Maxillofac Surg. 2009 May;67(5):1083-91. doi: 10.1016/j.joms.2008.09.032. — View Citation
Vegas-Bustamante E, Micó-Llorens J, Gargallo-Albiol J, Satorres-Nieto M, Berini-Aytés L, Gay-Escoda C. Efficacy of methylprednisolone injected into the masseter muscle following the surgical extraction of impacted lower third molars. Int J Oral Maxillofac Surg. 2008 Mar;37(3):260-3. doi: 10.1016/j.ijom.2007.07.018. Epub 2008 Mar 4. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Edema size measured by tape measure method | the effect of preemptive intravenous ibuprofen on postoperative edema size | 6 month | |
Secondary | Maximum mouth opening measured with vernier caliper | the effect of preemptive intravenous ibuprofen on postoperative trismus rate | 6 month |
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