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Trismus clinical trials

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NCT ID: NCT06193720 Completed - Pain Clinical Trials

The Impact of Arnica Montana Following the Surgical Extraction of Impacted Third Molars

Start date: February 3, 2022
Phase: N/A
Study type: Interventional

Aim: The aim of this study is to evaluate the action of the homeopathic plant Arnica Montana on postoperative edema, pain and trismus after surgical extraction of impacted wisdom teeth. Materials and Methods: The study is a double-blinded clinical trial recruiting patients undergoing surgical extraction of symmetrically impacted maxillary or mandibular third molars (right and left side). Patients receive alternately and randomly the verum (Arnica Montana 12 CH) or the placebo, in the form of capsules, to be taken 1 day prior to surgery and for 7 days postoperatively. Clinical parameters are collected and include: pain score, maximum mouth opening and facial measurements to assess edema's intensity.

NCT ID: NCT06148077 Not yet recruiting - Clinical trials for Head and Neck Cancer

Manual Therapy for Oral Health on Head and Neck Cancer Survivors

MaTeO
Start date: March 1, 2024
Phase: N/A
Study type: Interventional

Trismus has been reported as the second most common comorbidity in survivors of head and neck cancer (HNC). It is mainly associated with post-radiotherapy subcutaneous fibrosis, muscular atrophy, damage to neurological structures in the neck, or a combination of all, affecting masticatory musculature. In addition to this, the loss of flexibility and strength in the shoulder has also been shown to be related to deficits in the function and quality of life of these patients. The goal of this clinical trial is to determinate the effectiveness and safety of Manual Therapy (MT) on oral health, as well as the mobility of the upper quarter, the strength of cervical musculature, pain, functionality, and the perception of quality of life in head and neck cancer survivors. Participants will be assigned randomly to the study groups: a) manual therapy program and control motor exercises, b) control motor exercises (usual care) and, c) waiting list. The assessment refers to a baseline form (at the beginning of the study), at 6 weeks and at 6 weeks of patient follow-up.

NCT ID: NCT06073639 Active, not recruiting - Pain, Acute Clinical Trials

The Efficacy of Autogenous Dentin Graft in Mandibular Wisdom Tooth Extraction

Start date: December 1, 2021
Phase: N/A
Study type: Interventional

The study aimed to investigate clinical effect of autogenous dentin graft on patients following mandibular wisdom tooth extraction. The primary outcomes are pain, swelling, trismus and soft tissue healing index within one week after surgery. The investigators also measured periodontal healing of distal aspect of the adjacent second molar up to 2 year after the surgery.

NCT ID: NCT05992233 Completed - Molar, Third Clinical Trials

"Effectiveness of Dual-Wavelength Laser Therapy in Third Molar Extraction Pain, Swelling, and Trismus"

Start date: October 18, 2021
Phase: N/A
Study type: Interventional

Objective: To investigate the effects of single session dual wavelength low dose laser therapy to be applied after third molar tooth extraction on postoperative pain, edema and physical activities. Materials and Methods: Thirty-six patients who applied for the extraction of a Class III and position B lower impacted wisdom tooth were included in the study. The patients were divided into 2 groups as laser and control group. Envelope selection method was used for randomization of patients. After the surgery, a single session of double wavelength low-dose laser therapy was applied to the patients. On the 2nd and 7th postoperative days, pain was measured with the VAS scale, edema was measured by face measurements of 3 different points, and quality of life was measured with the modified Posse scale.

NCT ID: NCT05923775 Recruiting - Molar, Third Clinical Trials

Pain and Trismus Control in Third Molar Surgery: Ibuprofen, Ketamine, and Their Combination

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

The goal of the clinical trial is to compare the efficacy of ibuprofen, ketamine, and their combination in managing postoperative pain and trismus following third molar surgery. The main question it aims to answer is: which is the best way to control pain and trismus after third molar surgery?

NCT ID: NCT05777668 Completed - Trismus Clinical Trials

A Predictive Nomogram for Trismus After Radiotherapy for Head and Neck Cancer

Start date: January 2017
Phase:
Study type: Observational

Background: The aim of this study is to develop a prediction model for radiation-induced trismus (maximal interincisal distance equal to or less than 35 mm) based on a multivariable analysis of dosimetric and clinical factors.

NCT ID: NCT05757024 Recruiting - Trismus Clinical Trials

Effect Of High Power Laser On Radiotherapy Induced Trismus.

Start date: August 2, 2022
Phase: N/A
Study type: Interventional

this study Randomized controlled study will be conducted to study (the effect of high power laser therapy on radiotherapy induced trismus in head and neck cancer patients). the study group will receive high power laser therapy in combination with conventional tempromandibular joint exercises. the control group will receive conventional tempromandibular joint exercises.

NCT ID: NCT05752305 Completed - Pain, Postoperative Clinical Trials

Use of Corticosteroids in Third Molar Surgery

Start date: January 15, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

Surgical extraction of retained lower third molars is associated with the development of postoperative complications, including inflammation, trismus and postoperative pain, that lead to a decrease in patients' quality of life. Therefore, the use of drugs is essential to reduce the morbidity associated with surgery, with NSAIDs and corticosteroids being the most commonly used drugs.

NCT ID: NCT05679453 Completed - Pain, Acute Clinical Trials

Lornoxicam Versus Etodolac After Third Molar Surgery

Start date: July 20, 2022
Phase: Phase 4
Study type: Interventional

Our study aimed to compare the effect of lornoxicam and etodolac on postoperative pain, edema and trismus following lower third molar extraction

NCT ID: NCT05671861 Not yet recruiting - Clinical trials for Head and Neck Cancer

Evaluating a Low-Cost Therapeutic Device in Managing Head and Neck Cancer Patients With Radiation-Related Trismus

Start date: September 15, 2024
Phase: N/A
Study type: Interventional

This trial evaluates how well a new therapeutic device works in managing trismus in patients who received radiation treatment for head and neck cancer. Radiation therapy is a common form of treatment in patients with head and neck cancers. However, changes to surrounding tissue following radiation therapy may lead to trismus, an inability to open the mouth fully. This can create significant functional impairment leading to malnutrition due to impaired chewing, risk of dental infections due to impaired oral hygiene, difficulty with speech, and decreased health-related quality of life. Exercise therapy is the mainstay of treatment for post-radiation trismus to help improve mobility and flexibility and increase range of mouth opening. This new device is non-invasive and is similar to other jaw stretching devices where a mouthpiece is placed between the teeth and a hand-lever is used to spread open the upper and lower jaw. However, it will also have additional sensors to measure pressure exerted by the hands and jaw as well as the distance to open the mouth which could help guide therapy. This study may help doctors customize a device to patient-specific needs, provide real-time feedback, and encourage compliance for trismus exercise therapy.