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Eczema clinical trials

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NCT ID: NCT01246973 Completed - Clinical trials for Radiation-induced Dermatitis

Oral Curcumin for Radiation Dermatitis

Start date: February 2011
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of the study is to determine whether curcumin, an ingredient of some foods, can prevent or reduce the severity of skin reactions (dermatitis) caused by radiation therapy. Dermatitis is a common side effect of radiation treatment, but few effective treatments have been developed for it. Curcumin is a natural compound found in both turmeric and curry powder. It has been used for centuries as a spice (curry), a food coloring and as a food preservative. Curcumin is non-toxic and has been found to enhance the functions of normal tissues..

NCT ID: NCT01244607 Completed - Clinical trials for Allergic Contact Dermatitis

NI-0801 in Allergic Contact Dermatitis

Start date: n/a
Phase: Phase 1
Study type: Interventional

The purpose of the study is to assess the effect of a single dose of NI-0801 on the severity of nickel-induced allergic contact dermatitis.

NCT ID: NCT01244230 Completed - Atopic Dermatitis Clinical Trials

Safety, Efficacy and Pharmacokinetic Study of Allegra in Pediatric Patients With Atopic Dermatitis (AD)

Start date: November 2010
Phase: Phase 2/Phase 3
Study type: Interventional

Primary Objective: To evaluate safety (4 weeks) Secondary Objectives: - To evaluate the long-term safety (12 weeks) - To evaluate the efficacy - To characterize the pharmacokinetic profile

NCT ID: NCT01238263 Completed - Clinical trials for Atopic Dermatitis, Serum Skin Test

Autologous Serum Skin Testing in Patients With Atopic Dermatitis Autologous Serum Skin Testing in Patients With Atopic Dermatitis

Start date: April 2009
Phase: N/A
Study type: Observational

Recently, IgE-type autoantibodies against self proteins have been detected in the serum of the atopic dermatitis patients. The role of this IgE autoantibodies involved in the pathogenesis of atopic dermatitis is not known, yet. But, there may be a correlation between the severity of the disease and the serum levels of this autoantibodies. The autologous serum skin testing is applied to both atopic dermatitis patients and healthy control and the results are estimated in this study.The investigators detected 70% positive autologous serum skin testing in atopic dermatitis patients and test positivity was higher in patients with atopy history, moderately severe disease calculated by SCORAD index and high serum IgE levels.

NCT ID: NCT01232985 Completed - Atopic Dermatitis Clinical Trials

Efficacy and Tolerability Study of Device, RD047-26 for the Treatment of Mild to Moderate Atopic Dermatitis in Adults

Start date: October 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to find out if investigational device, RD047-26, is safe and useful for the treatment of mild to moderate atopic dermatitis.

NCT ID: NCT01232543 Completed - Atopic Dermatitis Clinical Trials

Safety Study Evaluating the Adrenal Suppression Potential of Product 0405 in Pediatric Subjects With Atopic Dermatitis

0405-01-04
Start date: November 2010
Phase: Phase 2
Study type: Interventional

The aim of the trial is to assess Adrenal Suppression potential when pediatric subjects are administered Product 0405 for the treatment of Atopic Dermatitis

NCT ID: NCT01228513 Completed - Atopic Dermatitis Clinical Trials

Efficacy and Safety of Different Concentrations of ZK245186 in Atopic Dermatitis (AD)

Start date: November 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of three concentrations of a development drug compared to placebo in the treatment of atopic dermatitis.

NCT ID: NCT01224132 Completed - Clinical trials for Atopic Dermatitis, Probiotics

Effect of Probiotics in the Atopic Dermatitis

Start date: October 2007
Phase: Phase 3
Study type: Interventional

This study was designed to evaluate the efficacy of probiotics in the treatment of atopic dermatitis. Probiotics in AD patients were effective in reducing SCORAD index levels, but not effective in skin prick test positivity, serum IL-2-4-5-6-10, TNF-α, IFN-γ, ECP, and serum total and specific IgE levels.

NCT ID: NCT01223222 Completed - Atopic Dermatitis Clinical Trials

A Study to Evaluate Safety, Tolerability and Efficacy of Lytixar™ (LTX-109) on Uncomplicated, Gram-positive, Skin Infection

Start date: September 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and tolerability of Lytixar™ applied topically to uncomplicated skin infections. Three dose levels of Lytixar™ (1%, 2% and 5%) versus placebo will be tested.

NCT ID: NCT01216059 Completed - Atopic Dermatitis Clinical Trials

Text Messaging and Atopic Dermatitis

Start date: October 2010
Phase: N/A
Study type: Interventional

Atopic dermatitis is a common problem faced by patients of all ages and backgrounds. Treatment regimens and specific therapies may be time consuming and multiple studies have documented a parallel decrease in compliance as time after an office visit increases. The adolescent population is an extremely challenging sub-group of patients in terms of complying with a treatment regimen. Not only are they striving for independence and thus lacking supervision of a regimen by a parent, but their complex thinking skills are immature, leading to forgetful behavior. By introducing a reminder system for these vulnerable patients that is easily incorporated into their daily lives, the investigators propose that patients will have better compliance at applying their medication and thus improving their atopic dermatitis. Text-messaging via cell phones has become very popular among teenagers and adults and provides a non-obtrusive method of sending a treatment reminder.