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Eclampsia clinical trials

View clinical trials related to Eclampsia.

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NCT ID: NCT03316430 Completed - Pre-Eclampsia Clinical Trials

Podocyturia as Predictive Factor for Pre-eclampsia

PEPOD1
Start date: May 15, 2019
Phase:
Study type: Observational

Pre-eclampsia is an hypertensive disorder appearing during pregnancy, inducing serious maternal, fetal and neonatal mortality and morbidity. Podocyn could be identified in the urine, before proteinuria, a key element in the diagnostic of pre-eclampsia. Preventive treatment using aspirin could be administrated in early pregnancy. We hypothesized that podocyturia could be an early indicator of preeclampsia. This is a prospective, non-interventional, monocentric study.

NCT ID: NCT03316391 Recruiting - Pre-Eclampsia Clinical Trials

Association Between Pococyturia and Pre-eclampsia Severity

PEPOD2
Start date: May 22, 2019
Phase:
Study type: Observational

Pre-eclampsia is an hypertensive disorder appearing during pregnancy, inducing serious maternal, fetal and neonatal mortality and morbidity. Twenty four hours proteinuria is a key element to define pre-eclampsia severity but is delaying the result by 24 hours and constraining for the patient. A simple and rapid indicator for severe preeclampsia would help clinicians to make appropriate decision in patient management. We hypothesized that urinary podocyturia is correlated to preeclampsia severity. This is a prospective, non-interventional, monocentric study.

NCT ID: NCT03302260 Not yet recruiting - Pre-Eclampsia Clinical Trials

Identifying Methods for Postpartum Reduction of Vascular Events: Pilot Randomized Controlled Trial

IMPROVE
Start date: September 2019
Phase: N/A
Study type: Interventional

IMPROVE is a pilot RCT with a behavioral intervention component (CardioPrevent program). The primary objectives of this pilot study are to assess the feasibility of the implementation of a postpartum CVD prevention lifestyle program in women with a HDP as well as the transferability and fidelity of the Ottawa-based CardioPrevent® program to a centre in Calgary (following a "Train the Trainer" model). Secondary objectives include an initial evaluation of the effectiveness of this intervention on clinical outcomes and measures of microvascular function between study arms at one year.

NCT ID: NCT03299777 Recruiting - Pre-Eclampsia Clinical Trials

Correlation Between Changes in Liver Stiffness and Preeclampsia as Shown by Fibroscan

Start date: September 5, 2017
Phase: N/A
Study type: Observational

Compare the Fibroscan results of preeclamptic women to normal controls and to find out if the changes are reversible after labor. Materials and Methods

NCT ID: NCT03298802 Recruiting - Pre-Eclampsia Clinical Trials

Postpartum Management of Hypertension in Pregnancy With Hydrochlorothiazide

Start date: November 21, 2017
Phase: Phase 3
Study type: Interventional

Postpartum prophylactic HCTZ administration for prevention and relapse of preeclampsia or gestational hypertension.

NCT ID: NCT03269110 Enrolling by invitation - Asthma Clinical Trials

Folic Acid Clinical Trial: Follow up of Children (FACT 4 Child)

Start date: July 1, 2017
Phase:
Study type: Observational

FACT 4 Child is a follow up study of mothers who participated in the Folic Acid Clinical Trial (NCT01355159) and their children at 4-6 years of age to determine the effect of high dose folic acid supplementation on social impairments associated with Autism Spectrum Disorders (ASDs), and deficiencies in a range of executive function and emotional and behavioural problems in young children, and the risk of death.

NCT ID: NCT03262961 Recruiting - Pre-Eclampsia; Mild Clinical Trials

Use of Sildenafil Citrate in Management of Mild Pre-eclampsia

Start date: September 15, 2016
Phase: Phase 2/Phase 3
Study type: Interventional

- Mild pre-eclampsia represents 75% of cases with pre-eclampsia, possible progression to severe pre-eclampsia makes mild pre-eclampsia a serious problem that requires attention. - Previous studies have shown that expectant and conservative management of pre-eclampsia in the context of extreme prematurity may improve perinatal outcomes. Indeed, it has been estimated that for each additional day of pregnancy prolongation between 24 and 32 weeks of gestation, there is a nonlinear corresponding gain of 1% in fetal survival. - Sildenafil citrate has been used for increasing utero-placental perfusion in cases with intrauterine growth restriction, which makes it a promising drug in management of mild pre-eclampsia.

NCT ID: NCT03252496 Completed - Cesarean Section Clinical Trials

Combined Colloids And Crystalloids Versus Crystalloids in Women With Preeclampsia Undergoing Cesarean Delivery

Start date: August 19, 2017
Phase: N/A
Study type: Interventional

This study will compare between combination of colloids/crystalloids and crystalloids in women with preeclampsia undergoing elective cesarean delivery under spinal anesthesia

NCT ID: NCT03246542 Completed - HELLP Syndrome Clinical Trials

Promising Bimarker Prediction of Outcome of HELLP Syndrome.

Start date: January 1, 2015
Phase: N/A
Study type: Observational [Patient Registry]

HELLP syndrome is a life-threatening obstetric complication usually considered to be a variant or complication of pre-eclampsia. And may occasionally be confused with other diseases complicating pregnancy such as acute fatty liver of pregnancy, gastroenteritis, hepatitis, appendicitis, gallbladder disease, immune thrombocytopenia, lupus flare, antiphospholipid syndrome, hemolytic-uremic syndrome, thrombotic thrombocytopenic purpura, and nonalcoholic fatty liver disease. The distinction between thrombotic thrombocytopenic purpura-hemolytic uremic syndrome and severe preeclampsia is important for therapeutic and prognostic reasons. However, the clinical and histological features are so similar that establishing the correct diagnosis is often difficult; furthermore, these disorders may occur concurrently.

NCT ID: NCT03233880 Recruiting - Pre-Eclampsia Clinical Trials

Impact of Antichlamydial Treatment on the Rate of Preeclampsia

Start date: July 1, 2016
Phase: Phase 4
Study type: Interventional

This randomized, double blinded controlled trial included 1200 healthy primigravidae who attended an outpatient clinic at 16-20weeks of pregnancy. All women were randomly divided equally into two groups, group A(600 women) who received antichlamydial treatment in the form of azithromycin 1 gram single oral dose before 20 weeks of pregnancy and group B (600 women) who received no treatment(placebo). All participants were followed up for up to 6 weeks postpartum and observed for the development of preeclampsia.