The Role of Neuromodulators in Refractory Functional Dyspepsia

Status Recruiting

Clinical Trial Summary

The study was designed to investigate the effect of central neuromodulators on refractory functional dyspepsia

Clinical Trial Description

Functional dyspepsia (FD) is a prevalent disease combined with emotional disorders. Antidepressants are beneficial in the treatment of refractory FD, while for the long-term use of antidepressants, it could lead to withdrawal syndrome or other adverse events. Refractory FD patients were unsatisfied with the regular first-line anti-acid treatment. However, many patients were worried about taking antidiepressants, even though guideline has recommended antidepressant use in FD. In our study, we would use low-dose and short-term antidepressant in refractory FD patients, and investigate whether short-term antidepressants application would improve therapeutic efficacy and minimize antidepressant withdrawal of FD patients. ;

Study Design

Related Conditions & MeSH terms

Antidepressant Drug Adverse Reaction
Digestive System Diseases
Drug-Related Side Effects and Adverse Reactions
Dyspepsia
Functional Gastrointestinal Disorders
Gastrointestinal Diseases
Syndrome

Clinical Trial Details

NCT number	NCT05099913
Study type	Interventional
Source	RenJi Hospital
Contact	Shengliang Chen, PhD
Phone	13916084817
Email	chensl@163.com
Status	Recruiting
Phase	N/A
Start date	August 1, 2020
Completion date	December 30, 2022

View Details

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