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Gustin Gene Polymorphism and 6-n-propylthiouracil (PROP) Taste — gustinprop  

Dysgeusia Clinical Trial

Official title:
Sensitivity to 6-n-propylthiouracil (PROP) Association With Gustin (CA6) Gene Polymorphism, Salivary Zinc and BMI in Humans

Clinical Trial Summary

The investigators evaluate the possible association of PROP taste with gustin gene polymorphism rs2274333 (A/G), salivary zinc ion concentration and BMI. In addition, it has also been evaluated PROP taste sensitivity by recording monophasic potentials from the tongue.

Clinical Trial Description

The investigators evaluate the possible association of PROP taste with gustin gene polymorphism rs2274333 (A/G), salivary zinc ion concentration and BMI.

Furthermore, we apply direct measures of the gustatory system activation following stimulation with PROP, obtained by electrophysiological recordings from the tongue of subjects classified for taster status, genotyped for the specific receptor gene (TAS2R38), and in which papilla density was determined. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01097915
Study type Observational
Source University of Cagliari
Contact
Status Completed
Phase
Start date October 2009
Completion date June 2016
View Details
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