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Clinical Trial Summary

The investigators wish to better understand the role of the choriocapillaris (CC) in the formation and progression of non-exudative in age related macular degeneration (armd) by imaging the retinal pigment epithelium (rpe) and the choroidal microvasculature and by studying their inter-dependence to determine if the loss of the CC could prove useful as an anatomic clinical trial endpoint in future drug trials.


Clinical Trial Description

This is a longitudinal observational study where the investigators will look at 450 subjects, 200 with intermediate AMD in at least one eye, or with AMD in one eye, either early or intermediate, and with late AMD (exudative) in the other eye, and 250 subjects with nGA or GA in at least one eye. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03688243
Study type Observational
Source Boston Image Reading Center
Contact
Status Active, not recruiting
Phase
Start date January 18, 2018
Completion date March 2023

See also
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Withdrawn NCT02024269 - Study to Assess the Safety and Effects of Cells Injected Intravitreal in Dry Macular Degeneration N/A
Completed NCT02684578 - Metformin for the Minimization of Geographic Atrophy Progression in Patients With AMD Phase 2