Dry Eye Syndrome Clinical Trial
Official title:
Influence of Lachrymal Substitutes on Tear Film Thickness in Patients With Moderate Dry Eye Syndrome
Dry eye syndrome is a highly prevalent ocular disease with an increasing incidence in the
elderly population. Topically administered lubricants are the basis for treatment of this
disease. However, information about the corneal residence time of topical lubricants is
still sparse, therefore no ideal treatment regimen has been found.
Recently a new method for assessment of tear film thickness based on optical coherence
tomography (OCT) has become available. The aim of the present study is to assess corneal
residence time of three different formulations of topical lubricants, in particular Thealoz
Duo® Eye Drops, Hyabak® Eye Drops and Hydrabak® Eye Drops in patients with moderate dry eye
disease. In addition, standard tests for dry eye syndrome, such as the ocular surface
disease index (OSDI©), Schirmer I test and determination of tear break up time (BUT) will be
performed..
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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