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Drug Usage clinical trials

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NCT ID: NCT06020391 Recruiting - Drug Usage Clinical Trials

Cooperation for Better Treatment of Polypharmacy in the Community

Start date: September 6, 2023
Phase: N/A
Study type: Interventional

The elderly population today relies heavily on medication consumption. While there are cases where using multiple medications is necessary and reasonable, it also increases the risk of inappropriate treatment and adverse drug effects. This randomized, controlled trial aims to examine the effectiveness of incorporating drug reviews as an integral part of clinical practice for older patients admitted to a Municipal in-patient acute care (MipAC) unit in Oslo, Norway. The intervention involves a clinical drug review conducted by a MipAC physician under the guidance of a geriatrician, followed by a telephone consultation between the MipAC physician and the patient's family physician (FP). The primary outcome measure is health-related quality of life, while secondary outcome measures include physical and cognitive function, dry mouth, hospital admissions, and survival. The environmental impact of the study intervention will also be assessed and compared to usual care.

NCT ID: NCT03938077 Withdrawn - Mental Health Clinical Trials

A Community-University Approach to Preventing HIV

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

Examine the feasibility and acceptability of delivering the S4E intervention to 20 African-American youths between the ages 16-21 in Flint, Michigan. The investigators will examine the preliminary efficacy of the S4E intervention in improving the uptake of HIV self-testing immediately post-intervention.

NCT ID: NCT03368456 Completed - Adolescent Behavior Clinical Trials

Preventing HIV/STI in Urban Adolescents Via an mHealth Primary Care Intervention

Start date: May 1, 2018
Phase: N/A
Study type: Interventional

The study evaluates the preliminary efficacy of an innovative mobile-health (mHealth) intervention (hereon referred to as S4E) to improve human immunodeficiency virus and sexually transmitted infection testing and reduce HIV/STI risk behaviors in a clinic sample (n=100) of at-risk youth ages 14-21 living in Southeast Michigan. A Stage I randomized control trial will be conducted to examine the preliminary efficacy of S4E, relative to Usual Care (UC), over a period of six months.

NCT ID: NCT03330782 Completed - Drug Usage Clinical Trials

Remifentanil for Preventing Propofol Injection Pain in Elderly Patients

Start date: November 16, 2017
Phase: Phase 4
Study type: Interventional

Elderly patients show different pharmacokinetic and pharmacodynamic variables and usually need smaller doses of anesthetic drugs than younger patients. The purpose of this study was to investigate the optimal effect-site concentration of remifentanil for preventing injection pain during propofol induction in elderly patients by the Dixon's up-and-down method.

NCT ID: NCT02973724 Completed - Drug Usage Clinical Trials

EC95 of Remifentanil for Preventing Cough

Start date: November 2016
Phase: N/A
Study type: Interventional

The investigator designed this study to investigate remifentanil effect-site concentration in 95% of patients (EC95) for preventing cough after laryngomicrosurgery from propofol anesthesia.

NCT ID: NCT02490345 Completed - Drug Usage Clinical Trials

Gabapentin as Adjunctive Treatment for Postoperative Pain Control

Start date: October 2015
Phase: Phase 1
Study type: Interventional

The specific aims of this research study are to use 600 mg gabapentin as an adjunctive treatment for acute postoperative pain control in order to reduce postoperative opiate consumption and improve postoperative pain control.

NCT ID: NCT02379455 Completed - Drug Usage Clinical Trials

Cooperation for Improved Pharmacotherapy in Home-dwelling Elderly People Receiving Polypharmacy - The COOP Study

COOP
Start date: March 2015
Phase: N/A
Study type: Interventional

Polypharmacy increases the risk of adverse drug effects, interactions and other drug-related problems, and several studies indicate that inappropriate drug use is a major reason for poor health and impaired function in the elderly. A majority of interventions for improvement of drug treatment in the elderly have been evaluated by the use of surrogate outcomes such as drug-related problems, number of prescribed drugs or prevalence of potentially inappropriate prescriptions - and it is so far unclear whether such interventions can result in clinical significant improvements. The primary objective of this trial is therefore to evaluate the effect upon patients, relatives and local health care service of a structured cooperation between a hospital-based geriatrician and family physicians on complex drug regimens in home-dwelling frail elderly patients.

NCT ID: NCT02334046 Completed - Drug Usage Clinical Trials

Remifentanil for Smooth Emergence in Elderly Patients

Start date: February 2015
Phase: Phase 4
Study type: Interventional

Elderly patients show different pharmacokinetic and pharmacodynamic variables and usually need smaller doses of anaesthetic drugs than younger patients. The purpose of this study was to investigate the optimal effect-site concentration of remifentanil for preventing cough during emergence in elderly patients under sevoflurane and remifentanil anesthesia.

NCT ID: NCT01963130 Completed - Drug Usage Clinical Trials

Does Vildagliptin Affect Portal Vein Pressure In Patients With Type 2 Diabetes Mellitus? A Cross Sectional Study

Start date: July 2012
Phase: N/A
Study type: Observational

This study investigated how vildagliptin (a di-peptidyl peptidase 4 inhibitor) affects portal vein pressure and hepatosteatosis in patients with type 2 diabetes mellitus.

NCT ID: NCT01931683 Completed - Drug Usage Clinical Trials

Dosing Study of Remifentanil for Smooth Removal of the Laryngeal Mask Airway (LMA)

Start date: October 2013
Phase: Phase 4
Study type: Interventional

The investigators attempted to determine the optimal effect-site concentration of remifentanil for smooth removal of the LMA from propofol anesthesia.