Clinical Trials Logo
  1. Home
  2. Drug Hypersensitivity
  3. NCT02839551

Optimal Doses for Drug Provocation Tests to Beta-lactams — NewBL  

Drug Hypersensitivity Clinical Trial

Official title:
Optimal Step Doses for Drug Provocation Tests to Prove Beta-lactam Hypersensitivity

Clinical Trial Summary

Drug provocation tests (DPT) are widely in case of suspicion of drug hypersensitivity (and in the absence of contraindications), but there are no standardized protocols and most groups use hypothesis (clinically-driven) protocols. investigators used 20 year experience in drug hypersensitivity to analyse retrospectively 171 patients (accounting for 182 positive DPT to beta-lactams). Using survival analysis, they identified optimal doses to include in a data-driven protocol. This data-driven protocol will be applied to new prospective patients, to test its safety and benefits (gain in time, hospital and patient benefits).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02839551
Study type Interventional
Source University Hospital, Montpellier
Contact
Status Completed
Phase N/A
Start date May 4, 2016
Completion date November 16, 2021
View Details
See also
  Status Clinical Trial Phase
Completed NCT00198419 - Hypersensitivity Reaction to Vitrase (Ovine Hyaluronidase) Phase 1
Completed NCT02839811 - Medical Device for Drug Allergy Diagnosis N/A
Completed NCT02983630 - Allergy Testing of Patients Labeled as Penicillin Allergic N/A
Completed NCT00198458 - Hypersensitivity Reaction to Vitrase (Ovine Hyaluronidase) Phase 1
Recruiting NCT04330118 - Origin and Function of Eosinophilic Polynuclear During DRESS Syndrome
Completed NCT04421638 - Cephalosporin Hypersensitivity
Recruiting NCT02031120 - Management of Drug Hypersensitivity in Children N/A
Completed NCT01276314 - Evaluation of TNF-α Blockade Effect in Patients With Severe Cutaneous Adverse Drug Reactions N/A
Terminated NCT00505648 - Treatment of Hypersensitivity Syndrome (DRESS) With Tegeline® (Human Immunoglobulin) Phase 3
Completed NCT03158831 - Drug Challenges Without Prior Skin Testing Phase 1
Completed NCT03076749 - Predictive Models for Betalactam Allergy N/A
Active, not recruiting NCT06428162 - An Evaluation of Healthcare Providers' Adherence to Pharmacovigilance Practices in an African Community
Terminated NCT02844712 - Negative Predictive Value of Drug Provocation Tests to Beta-lactams N/A
Completed NCT03771118 - Drug Provocation Test (DPT) to Paracetamol
Completed NCT03743220 - Drug Provocation Test (DPT) to Non Steroidal Anti-inflammatory Drugs (NSAID)
Not yet recruiting NCT06406114 - Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing Phase 2
Completed NCT05269082 - A Study to Assess the Hypersensitivity to TAK-880 Compared to Gammagard S/D in Blood of Children, Teenagers and Adults
Completed NCT04827602 - Drug Allergy Labels After Drug Allergy Investigation