Construction of Early Warning Model for the New Psychoactive Substances Using in Adolescents

Drug Addiction Clinical Trial

Official title:

Early Warning Model Construction on Cognition, Resistance and Using Risk of the New Psychoactive Substances in Adolescents Based on Behavioral Expression of Addiction Susceptibility Genes and Adverse Childhood Experience

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05958641
• Other study ID #: 202310893
• Status: Not yet recruiting
• Start date: July 17, 2023
• Est. completion date: November 30, 2023

Study information

• Verified date: July 2023
• Source: Sun Yat-sen University
• Contact: Wei Xia, PhD
• Phone: 18823359471
• Email: xiaw23[@]mail.sysu.edu.cn
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Based on the biological-psychology-sociological medicine pattern, this study aims to construction an early warning model of the New Psychoactive Substances (NPS) using for adolescents aged 14-35 years old. This study intends to obtain the data related to the behavioral expression of addiction susceptibility genes, adverse childhood experience, cognition, resistance and the use of NPS in adolescents by questionnaire survey (sample size: 200), and then use logistic regression and machine learning to construct an early warning model.

Description:

Based on the biological-psychology-sociological medicine pattern, this study aims to construction an early warning model on the use of the New Psychoactive Substances using for adolescents aged 14-35 years old. This study intends to conduct a questionnaire survey (sample size 200) to obtain data related to the behavioral expression of addiction susceptibility genes, childhood adversity experience, cognition, resistance and the use of NPS in adolescents from different regions and different populations. Through data analysis, this study aims to get the weight of different risk factors on NPS use, and then use logistic regression and machine learning to construct an early warning model, so as to screen out high-risk groups. At the same time, the expert group was consulted to establish a risk early warning system to provide a basis for intervention.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 200
• Est. completion date: November 30, 2023
• Est. primary completion date: October 31, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 14 Years to 35 Years

Eligibility

Inclusion Criteria:

• Adolescents aged 14-35 (including 14,35 years old)

• Agree to participate in the studies

Exclusion Criteria:

• Be diagnosed with psychological or mental illness

• People that are unconscious, emotionally unstable, or unable to communicate normally

• Patients with severe diseases

Related Conditions & MeSH terms

• Behavior, Addictive
• Drug Addiction
• Substance-Related Disorders

Intervention

Other:
• Questionnaires
Participants will be asked to complete the questionnaire including general demographic information, the cognition, resistance and use of NPS as well as the behavioral expression of addiction susceptibility genes and adverse childhood experience.

Locations

Country	Name	City	State
China	Sun Yat-sen University	Guangzhou	Guangdong

Sponsors (1)

Lead Sponsor	Collaborator
Wei XIA, PhD

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	the cognition of NPS	knowledge questionnaire of drug types and risk awareness of drug use will be investigated to know the degree of cognition to NPS	Baseline
Primary	the resistance of NPS	the drug refusal self-efficacy scale and the drug use permissive attitude will be used to measure the the resistance of NPS	Baseline
Primary	the use of NPS	there will be some questions to investigate the drug use conditions	Baseline
Primary	Adverse Childhood Experience	the Chinese version of Adverse Childhood Experience Scale with 10 items will be used to measure the adverse childhood experience	Baseline
Primary	hedonic hunger	the Power of Food Scale with 15 items will be used to measure hedonic hunger	Baseline
Primary	sensation seeking personality	the Brief Sensation Seeking Scale for Chinese with 8 items will be used to measure sensation seeking personality	Baseline
Primary	prosocial behavior	the Prosocial Tendencies Measure with 26 items will be used to measure prosocial behavior	Baseline
Primary	externalizing behavior	17 items of aggressive behavior and 15 items of rule-breaking behavior from the Chinese Version of Achenbach Youth Self-Report-2001 Version will be used to measure adolescents' degree of externalizing behavior	Baseline
Primary	sleep quality	the Pittsburgh Sleep Quality Index with 9 items will be used to measure adolescents' sleep quality	Baseline