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Naloxone Nasal Spray Compared With Naloxone Injection for Opioid Overdoses Outside the Hospital — NINA-1  

Drug Abuse Clinical Trial

Official title:
NTNU Intranasal Naloxone Trial - a Double Blinded, Double Dummy, Randomized Controlled Trial of Intranasal Naloxone for Pre-hospital Use

Clinical Trial Summary

This trial will compare the clinical response to intramuscular and intranasal naloxone in pre-hospital opioid overdoses. Objective of the study is to measure and evaluate clinical response (return of spontaneous respiration within 10 minutes of naloxone administration) to a new nasal naloxone formulation in real opioid overdoses in the pre-hospital environment. The aim is to demonstrate that intranasal administration of naloxone is not clinically inferior to intramuscular administration, which is now standard treatment of care.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03518021
Study type Interventional
Source Norwegian University of Science and Technology
Contact
Status Completed
Phase Phase 3
Start date May 15, 2018
Completion date October 6, 2020
View Details
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