Exercise Intensity for Down Syndrome Children

Down Syndrome Clinical Trial

Official title:

Effect of Exercise Intensity on Knee and Ankle Joints' Torque and Functional Mobility in Children With Down's Syndrome: a Randomized Controlled Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05271201
• Other study ID #: 291
• Status: Completed
• Phase: N/A
• Start date: December 10, 2019
• Est. completion date: March 27, 2020

Study information

• Verified date: February 2022
• Source: Taif University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The current study aimed to determine the appropriate exercise intensity for the rehabilitation of children with down syndrome.

Description:

Two groups of down syndrome children were recruited. one group received mild-intensity treadmill training while the other received moderate-intensity treadmill training. Eccentric knee extensors and ankle plantar flexors peak torques were assessed before and after the intervention. Also, functional mobility was assessed for both groups before and after the intervention. The within and between-subjects effect was used to analyze the obtained data before and after the intervention. isokinetic dynamometer and the time up and go test were used for evaluation.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 34
• Est. completion date: March 27, 2020
• Est. primary completion date: March 15, 2020
• Accepts healthy volunteers: No
• Gender: Male
• Age group: 8 Years to 12 Years

Eligibility

Inclusion Criteria:

• independent walking

• Intelligence quotient range from 40 to 70

• right dominant foot

• body mass index from 50 to 75

Exclusion Criteria:

• chronic diseases

• congenital anomalies

• involved in any competitive sport

• previous injury to the lower limb

Related Conditions & MeSH terms

• Down Syndrome
• Syndrome

Intervention

Other:
• treadmill exercise (mild)
mild intensity treadmill training.
• treadmill exercise (moderate)
moderate-intensity treadmill training

Locations

Country	Name	City	State
Saudi Arabia	College of Applied Medical Sciemces	Ta'if	Mecca

Sponsors (1)

Lead Sponsor	Collaborator
Taif University

Country where clinical trial is conducted

Saudi Arabia, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	knee extensor peak torque	eccentric normalized peak torque of the knee extensors of the dominant limb.	three months
Primary	ankle plantar fexors peak torque	eccentric normalized peak torque of the ankle plantar flexors of the dominant limb.	three months
Primary	functional mobility	the assessment of the time up and go test	three months