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Pediatric Exploratory Research Study of EGCG Use and Safety (PERSEUS) — PERSEUS  

Down Syndrome Clinical Trial

Official title:
Pediatric Exploratory Research Study of EGCG Use and Safety (PERSEUS)

Clinical Trial Summary

To evaluate safety and tolerability of epigallocatechin gallate (EGCG) in children from 6 to 12 years old with Intellectual Developmental Disorders (IDD) (Down syndrome or Fragile X syndrome).

Clinical Trial Description

This project first objective is to evaluate the safety and tolerability of the EGCG molecule (extracted form green tea) on children from 6 to 12 years old with Intellectual Development Disorder (Down syndrome and Fragile X syndrome). The secondary objective is to evaluate the benefits of the EGCG on attention, memory, executive functions, language and adaptive behaviour of these children. Dyrk1A and homocysteine in plasma will also be quantified, using them as biomarkers of efficacy. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03624556
Study type Interventional
Source Parc de Salut Mar
Contact
Status Completed
Phase N/A
Start date January 29, 2018
Completion date November 30, 2020
View Details
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