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Safety, Tolerability and Immunogenicity of ACI-24 Vaccine in Adults With Down Syndrome — 3-Star  

Down Syndrome Clinical Trial

Official title:
A Phase Ib Multi-Center, Double-Blind, Randomized, Placebo-Controlled Dose Escalation Study of the Safety, Tolerability and Immunogenicity of ACI-24 in Adults With Down Syndrome

Clinical Trial Summary

The purpose of this study is to test in adults with Down Syndrome the safety, tolerability and immunogenicity of a vaccine, ACI-24.

Clinical Trial Description

This is a prospective multi-center, placebo controlled, double-blind and randomized dose escalation study of 2 doses of ACI-24 versus Placebo over 24 months with a total of 21 visits. All subjects will receive the study medication (ACI-24 or Placebo) 7 times via s.c. injection (12 months) and will be followed up for 12 months after the last dose with a final safety and efficacy assessment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02738450
Study type Interventional
Source AC Immune SA
Contact
Status Completed
Phase Phase 1
Start date March 2016
Completion date June 2020
View Details
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