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Diving Medicine clinical trials

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NCT ID: NCT03190252 Completed - Inflammation Clinical Trials

Inflammatory and Cerebrospinal Biochemical Markers in Blood After Trimix Diving

TriMix17-18
Start date: June 12, 2017
Phase:
Study type: Observational

Research hypothesis - Diving to depths up to 90msw with an oxygen partial pressure of 130kPa in the breathing gas will affect the central nervous system. - Diving to depths up to 90msw with an oxygen partial pressure of 130kPa in the breathing gas will induce inflammatory changes. Objectives: - To investigate the presence of cerebrospinal biochemical markers in blood after diving to depths up to 90msw with an oxygen partial pressure of 130kPa in the breathing gas. - To investigate the presence of inflammatory markers in blood after diving to depths up to 90msw with an oxygen partial pressure of 130kPa in the breathing gas. - To investigate the presence of venous gas emboli (VGE) in blood after diving to depths up to 90msw with an oxygen partial pressure of 130kPa in the breathing gas.

NCT ID: NCT02468752 Completed - Inflammation Clinical Trials

Reduction of Venous Emboli Load After Breathing Normobaric Oxygen Compared to Air

Start date: May 2015
Phase: Phase 2/Phase 3
Study type: Interventional

Primary objective: - Assessment of venous gas emboli load post diving when breathing normobaric oxygen compared to air. Secondary objective: - Assessment of fluid markers of central nervous system injury in blood post diving - Assessment of fluid markers of inflammation and endothelial dysfunction in blood post diving Tertiary objective: - Assessment of DCS frequency