Clinical Trials Logo

Clinical Trial Summary

The goal of this prospective, exploratory and observational study is to learn about in healthy volunteers and patients with prolonged disorders of consciousness(pDoC). The main questions it aims to answer are: 1. Observe the similarities and differences of polysomnography between pDoC patients and healthy volunteers, and analyze the characteristic brain network changes based on polysomnography 2. To observe the similarities and differences of polysomnography in pDoC patients before and after Insertion of spinal cord electric stimulator under general anesthesia,and analyze the changes of anesthesia characteristic brain network in patients with consciousness disorders based on polysomnography. 3. To observe the similarities and differences of polysomnography in pDoC patients before and after spinal cord stimulation,and analyze the characteristic changes of brain network after spinal cord stimulation. We will record the 8h polysomnography of healthy volunteers,record the polysomnography of DOC patients before and 24 hours after operation;and record the 24h polysomnography of patients with spinal cord electric stimulator.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06157008
Study type Observational
Source Beijing Tiantan Hospital
Contact Ruquan Han, M.D
Phone 8610-59976660
Email ruquan.han@ccmu.edu.cn
Status Recruiting
Phase
Start date January 11, 2023
Completion date June 1, 2024

See also
  Status Clinical Trial Phase
Recruiting NCT06076733 - Intervention Effect of Transcranial Alternating Current Stimulation (tACS) on Disorder of Consciousness (DOC) N/A
Recruiting NCT05558670 - Brain Network Characteristics in Patients With Disorders of Consciousness
Completed NCT02424656 - Alterations in the Brain's Connectome After Severe Traumatic Brain Injury
Completed NCT02879565 - Families Expectations and Hope Raised by an Evaluation of Consciousness in Patients in a Vegetative State N/A
Completed NCT02759068 - Beneficial Effects of Preference on Behavior in DOC Patients (COGNICOMA) N/A
Not yet recruiting NCT06323031 - Spontaneous Eye Blinking in Disorders of Consciousness
Terminated NCT02732288 - Exploratory Study of Melatonin Induced Sleep Regularization in Severe Brain Injury N/A
Completed NCT03115021 - Neurophysiological Effects of tPCS and tDCS on Patients With Disorders of Consciousness Phase 1
Not yet recruiting NCT06167200 - Validation of a Clinical Complications Scale (CCS) in Patients With Disorders of Consciousness
Recruiting NCT04798456 - Aiming for a Better Understanding and Improvement of the Diagnosis and Prognosis of Patients With Disorders of Consciousness Through Multimodal Observations
Recruiting NCT04706689 - Development and Validation of the SWADOC Tool
Completed NCT02394691 - Effect of Repeated tDCS Sessions on Cognitive Improvement in Patients With Disorders of Consciousness N/A
Completed NCT02639481 - Erigo®Pro Coma Outcome Study - Study on the Effectiveness of a Robotic Tilt Table Device for Recovery of Consciousness Phase 3
Not yet recruiting NCT02628639 - Optimizing the Evaluation of Awareness in Disorders of Consciousness N/A
Completed NCT02930213 - The Core Body Temperature Rhythms: Distinguishing MCS From UWS Phase 2
Completed NCT02626403 - Fronto-parietal tDCS in Severely Brain Injured Patients With Disorders of Consciousness N/A
Completed NCT01673126 - Transcranial Direct Current Stimulation in Patients With Disorders of Consciousness Phase 2
Completed NCT04330547 - Use of Analgesic Treatment to Reduce Signs of Pain in Patients With Disorders of Consciousness. Phase 1
Recruiting NCT06204172 - Intensive Neurowave Emotional Stimulation (INES) N/A
Recruiting NCT05949528 - Clinical Evaluation of Chronic Consciousness Disorders Using Resting-state EEG and ERP