Cardiovascular Responses to Spartathlon Running

Disorder Heart Clinical Trial

— Spartathlon  

Official title:

Cardiovascular Effects of Ultramarathon Running

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03304483
• Other study ID #: 84542
• Status: Completed
• Phase: N/A
• Start date: September 29, 2017
• Est. completion date: June 30, 2021

Study information

• Verified date: July 2023
• Source: Aristotle University Of Thessaloniki
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of this study is to examine the cardiovascular effects of ultramarathon running and their relation to performance.

Description:

The purpose of the study is to determine the changes of cardiovascular morphology and function after an ultramarathon race. 50 entrants to the "Spartathlon 2017" 246-km running race will participate in the study. Cardiac and arterial morphology and function tests will be conducted one day before the race and within 20 minutes of race completion.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 50
• Est. completion date: June 30, 2021
• Est. primary completion date: December 30, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 67 Years

Eligibility

Inclusion Criteria:

• Runners at least 18 years old, healthy and sufficiently trained.

• Runners being accepted to participate in the Spartathlon race according to the eligibility criteria (http://www.spartathlon.gr/en/registration-en.html)

• Runners who will volunteer to be examined pre- and post the race

Exclusion Criteria:

• Runners with chronic diseases

• Runners receiving any medication

Related Conditions & MeSH terms

• Disorder Heart
• Heart Diseases

Intervention

Other:
• 246-km running
Spartathlon 2017

Locations

Country	Name	City	State
Greece	Laboratory of Sports Medicine	Thessaloniki

Sponsors (1)

Lead Sponsor	Collaborator
Aristotle University Of Thessaloniki

Country where clinical trial is conducted

Greece, 

References & Publications (5)

Blaber AP, Walsh ML, Carter JB, Seedhouse EL, Walker VE. Cardiopulmonary physiology and responses of ultramarathon athletes to prolonged exercise. Can J Appl Physiol. 2004 Oct;29(5):544-63. doi: 10.1139/h04-035. — View Citation

Cote AT, Phillips AA, Foulds HJ, Charlesworth SA, Bredin SS, Burr JF, Koehle MS, Warburton DE. Sex differences in cardiac function after prolonged strenuous exercise. Clin J Sport Med. 2015 May;25(3):276-83. doi: 10.1097/JSM.0000000000000130. — View Citation

Jee H, Park J, Oh JG, Lee YH, Shin KA, Kim YJ. Effect of a prolonged endurance marathon on vascular endothelial and inflammation markers in runners with exercise-induced hypertension. Am J Phys Med Rehabil. 2013 Jun;92(6):513-22. doi: 10.1097/PHM.0b013e31829232db. — View Citation

Millet GP, Millet GY. Ultramarathon is an outstanding model for the study of adaptive responses to extreme load and stress. BMC Med. 2012 Jul 19;10:77. doi: 10.1186/1741-7015-10-77. — View Citation

Seedhouse EL, Walsh ML, Blaber AP. Heart rate, mean arterial blood pressure, and pulmonary function changes associated with an ultraendurance triathlon. Wilderness Environ Med. 2006 Winter;17(4):240-5. doi: 10.1580/pr27-05-r1.1. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change of right ventricular function after one day ultra-marathon running	Echocardiographic study of left ventricular function	before and after 1 day running
Secondary	Change of left ventricular function after one day ultra-marathon running	Echocardiographic study of left ventricular function	before and after 1 day running
Secondary	Change of carotid artery function after one day ultra-marathon running	Echocardiographic study of carotid arteries	before and after 1 day running