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Study to Evaluate the Efficacy of Ruxolitinib 1.5% Cream in Adult Subjects With Discoid Lupus Erythematosus

Discoid Lupus Erythematosus Clinical Trial

Official title:
A Phase 2, Single-Blind, Intraindividual Study to Evaluate the Efficacy of Ruxolitinib 1.5% Cream in Adult Subjects With Discoid Lupus Erythematosus

Clinical Trial Summary

This study is a single-blind, intraindividual study to evaluate the efficacy of ruxolitinib 1.5 % cream in adult subjects with discoid lupus erythematosus.

Clinical Trial Description

This study is being conducted to evaluate the efficacy, safety and tolerability of ruxolitinib 1.5 % cream in adult subjects with discoid lupus erythematosus. Approximately 20 subjects with discoid lupus erythematosus will apply ruxolitinib 1.5% cream, twice daily on active lesions identified at Day 1 and any new lesions that appear, for 24 weeks. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06261021
Study type Interventional
Source Innovaderm Research Inc.
Contact Fareheen Chowdhury
Phone 514-521-4285
Email fchowdhury@innovaderm.com
Status Recruiting
Phase Phase 2
Start date April 19, 2024
Completion date February 2025
View Details
See also
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Recruiting NCT05591222 - Study of Daxdilimab (HZN-7734) in Patients With Moderate-to-Severe Primary Discoid Lupus Erythematosus Phase 2
Completed NCT00625521 - Efficacy and Safety of ASF-1096 Cream 0.5% in the Treatment of Discoid Lupus Erythematosus (DLE) Lesions Phase 2
Completed NCT04908280 - Study of Ruxolitinib Cream for the Treatment of Discoid Lupus Erythematosus Phase 2
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Completed NCT00708916 - Safety Study of Clinical and Immune Effects of Phosphodiesterase 4 (PDE-4) Inhibitor in Cutaneous Lupus Patients Phase 1/Phase 2
Terminated NCT03958955 - Efficacy and Safety of Delgocitinib Cream in Discoid Lupus Erythematosus. Phase 2
Terminated NCT03159936 - Oral Tofacitinib in Adult Subjects With Discoid Lupus Erythematosus (DLE) and Systemic Lupus Erythematosus (SLE) Early Phase 1
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Completed NCT00608673 - Comparing the Therapeutic Efficacy of Pimecrolimus Cream With Betamethasone Cream for Discoid Lupus Erythematosus N/A
Completed NCT00625157 - Efficacy and Safety of ASF-1096 Cream 0.5% in the Treatment of Discoid Lupus Erythematosus (DLE) Lesions (2) Phase 2