Diminished Ovarian Reserve Clinical Trial
Official title:
Efficacy of Thumb-tack Needle Treatment for Diminished Ovarian Reserve: Study Protocol for a Randomized Controlled Trial
Diminished Ovarian Reserve (DOR) is characterized as an important cause of infertility. Acupuncture has been extensively used to treat female infertility. This study was conducted to investigate the efficacy of thumb-tack needle，as a new special type of acupuncture and long-lasting treatment modality,in the treatment of DOR.
There will be a multi-center, randomized, sham-controlled trial. 106 patients will be randomly assigned into thumb-tack needle acupuncture or sham-acupuncture in 1:1 ratio. All the patents will achieve 12 sessions of verum or sham treatments in 20 weeks(12 weeks for treatment and 8 weeks for follow-up). Patients, outcome assessors and statisticians are masked from group assignment. The study is aim to evaluate the efficacy of thumb-tack needle for DOR. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04972877 -
Effect of Electro-acupuncture on Women With Diminished Ovarian Reserve
|
N/A | |
| Recruiting |
NCT04447872 -
The LUTEAL Trial: Luteal Stimulation vs. Estrogen Priming Protocol
|
N/A | |
| Recruiting |
NCT05277948 -
Effect of Thumbtack Needle on Ovarian Function of Women With Diminished Ovarian Reserve (DOR)
|
N/A | |
| Recruiting |
NCT04711772 -
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve
|
||
| Recruiting |
NCT03670407 -
Follicular Activation by Fragmentation of Ovarian Tissue
|
N/A | |
| Recruiting |
NCT06072794 -
A Proof of Concept Study to Evaluate Exosomes From Human Mesenchymal Stem Cells in Women With Premature Ovarian Insufficiency (POI)
|
Phase 1 | |
| Recruiting |
NCT06096766 -
the Correlation Between Ovarian Function and Serum Biomarkers
|
||
| Not yet recruiting |
NCT02099916 -
Administration of DHEA in Patients With Poor Response to Ovarian Stimulation for IVF
|
Phase 2/Phase 3 | |
| Not yet recruiting |
NCT06081257 -
The Effect of "KB-120" Small Molecular Nutrient in Women With Decreased Ovarian Reserve
|
N/A | |
| Recruiting |
NCT04275700 -
Study of PRP in Women With Evidence of Diminished Ovarian Reserve
|
N/A | |
| Not yet recruiting |
NCT05577455 -
Efficacy of Traditional Chinese Medicine on Ameliorating IVF-ET Outcomes of Diminished Ovarian Reserve Patients
|
Phase 3 | |
| Not yet recruiting |
NCT05459493 -
A Clinical Study of Chinese Herbal Compound TJAOA101 in Therapy of Diminished Ovarian Reserve
|
Early Phase 1 | |
| Recruiting |
NCT05665010 -
Precise Stratification of Genetic Risk of Ovarian Function Impairment
|
||
| Not yet recruiting |
NCT05385848 -
Autologous Platelet-rich Plasma (PRP) Infusion to Improve Outcomes in Women With Ovarian Insufficiency: a Pilot Study
|
N/A | |
| Terminated |
NCT01614067 -
Delayed Start to Ovarian Stimulation
|
Phase 4 | |
| Recruiting |
NCT06395623 -
Study of Acupoints in Diminished Ovarian Reserve Based on Biological Characteristics
|
||
| Recruiting |
NCT05847283 -
DPOS Versus GnRH Antagonist Protocol for Oocyte Accumulation in Low Ovarian Reserve Patients: An RCT
|
N/A | |
| Recruiting |
NCT05485610 -
Effect of NMN (Nicotinamide Mononucleotide) on Diminished Ovarian Reserve (Including Premature Ovarian Insufficiency)
|
N/A | |
| Completed |
NCT04237909 -
Effects of Intraovarian Platelet Rich Plasma in Women With Poor Ovarian Response and Premature Ovarian Insufficiency
|
N/A | |
| Recruiting |
NCT04278313 -
Ovarian Function Following Intraovarian Injection of PRP
|
N/A |