Validating eNose Measurement of Daily Fiber Intake

Status Active, not recruiting

Clinical Trial Summary

Monitoring dietary intake and digestion is important for both medical monitoring and assessing the wellness of individuals. Fiber is an important nutrient that is not focused on enough, despite it being an essential nutrient for the bacteria and other micro-organisms that reside in our GI Tracts, known as the microbiome. Ingestion of fermentable soluble and insoluble dietary fiber has been shown to result in the production of short-chain fatty acids (SCFA) by the colonic microbiome. These SCFAs are volatile organic compounds (VOCs) and can be detected in the atmosphere of a bowel movement. We have developed an e-Nose device that once placed in the bathroom records volatile organic compounds (VOCs) from the ambient air. We have demonstrated in an "N of 1" study a strong correlation between the eNose output and grams of daily fiber intake. The current study is being proposed to validate the e-Nose device on a larger population. This is a nonmedical device that is not regulated by the FDA. A total of 40 subjects are invited to participate in this 3-week study. Participants will be asked to complete questionnaires and provide stool and blood samples. The subjects will place the eNose device in their bathroom and record their daily food intake over a 3-week period.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Dietary Fiber

Clinical Trial Details

NCT number	NCT05634044
Study type	Interventional
Source	Rush University Medical Center
Contact
Status	Active, not recruiting
Phase	N/A
Start date	November 8, 2022
Completion date	June 2024

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT05726435` - Effects of Soluble Dietary Fiber on Sport Efficiency and Fatigue Delay in Top Basketball Players	N/A
Recruiting	`NCT04499183` - Fiber Fermentation, and Short Chain Fatty Acid Kinetics and Utilization Inside the Gut and Systemic Circulation	N/A
Completed	`NCT03848546` - Stimulating Fiber Intake Via Personalized Dietary Advice	N/A
Completed	`NCT04013607` - Fiber Fermentation Kinetics Inside the Gut, and Utilization of Bacterial Metabolites	N/A
Withdrawn	`NCT04438473` - Pectin Supplemented Enteral Feedings in Critically Ill Patients	N/A
Completed	`NCT04352231` - Luxembourgish Fiber Cohort	N/A
Completed	`NCT03387345` - Barley and Rice Mixture Effects on Blood Glucose	N/A
Recruiting	`NCT04690075` - Effect of Dietary Fiber on Metabolism, Inflammation and Nutritional Status in Patients With Chronic Diseases	N/A
Completed	`NCT03796286` - A Randomized, Crossover Study to Assess the Effects of Dietary Fiber-containing Bars on Glucose and Insulin Responses	N/A
Recruiting	`NCT04611217` - Dietary Fiber Effects on the Microbiome and Satiety	N/A
Completed	`NCT01321736` - Gut Health Response to Dietary Fiber	N/A