Outcome
Type |
Measure |
Description |
Time frame |
Safety issue |
Primary |
Forearm blood flow |
Doppler ultrasound - tested at rest and during rhythmic handgrip exercise with and without lower body negative pressure |
Baseline - Immediately before active and control interventions |
|
Primary |
Forearm blood flow |
Doppler ultrasound - tested at rest and during rhythmic handgrip exercise with and without lower body negative pressure |
Immediately after active and control interventions (IPC only) |
|
Primary |
Forearm blood flow |
Doppler ultrasound - tested at rest and during rhythmic handgrip exercise with and without lower body negative pressure |
1 hour after active and control interventions (Diet intervention only) |
|
Primary |
Forearm blood flow |
Doppler ultrasound - tested at rest and during rhythmic handgrip exercise with and without lower body negative pressure |
2 hours after active and control interventions (Diet intervention only) |
|
Primary |
Forearm blood flow |
Doppler ultrasound - tested at rest and during rhythmic handgrip exercise with and without lower body negative pressure |
3 hours after active and control interventions (Diet intervention only) |
|
Primary |
Forearm vascular conductance |
Blood flow divided by blood pressure - tested at rest and during rhythmic handgrip exercise with and without lower body negative pressure |
Baseline - Immediately before active and control interventions |
|
Primary |
Forearm vascular conductance |
Blood flow divided by blood pressure - tested at rest and during rhythmic handgrip exercise with and without lower body negative pressure |
Immediately after active and control interventions (IPC only) |
|
Primary |
Forearm vascular conductance |
Blood flow divided by blood pressure - tested at rest and during rhythmic handgrip exercise with and without lower body negative pressure |
1 hour after active and control interventions (Diet intervention only) |
|
Primary |
Forearm vascular conductance |
Blood flow divided by blood pressure - tested at rest and during rhythmic handgrip exercise with and without lower body negative pressure |
2 hours after active and control interventions (Diet intervention only) |
|
Primary |
Forearm vascular conductance |
Blood flow divided by blood pressure - tested at rest and during rhythmic handgrip exercise with and without lower body negative pressure |
3 hours after active and control interventions (Diet intervention only) |
|
Secondary |
Blood pressure |
Finger plethysmography - tested at rest and during rhythmic handgrip exercise with and without lower body negative pressure |
Baseline - Immediately before active and control interventions |
|
Secondary |
Blood pressure |
Finger plethysmography - tested at rest and during rhythmic handgrip exercise with and without lower body negative pressure |
Immediately after active and control interventions (IPC only) |
|
Secondary |
Blood pressure |
Finger plethysmography - tested at rest and during rhythmic handgrip exercise with and without lower body negative pressure |
1 hour after active and control interventions (Diet intervention only) |
|
Secondary |
Blood pressure |
Finger plethysmography - tested at rest and during rhythmic handgrip exercise with and without lower body negative pressure |
2 hours after active and control interventions (Diet intervention only) |
|
Secondary |
Blood pressure |
Finger plethysmography - tested at rest and during rhythmic handgrip exercise with and without lower body negative pressure |
3 hours after active and control interventions (Diet intervention only) |
|
Secondary |
Heart rate |
ECG - tested at rest and during rhythmic handgrip exercise with and without lower body negative pressure |
Baseline - Immediately before active and control interventions |
|
Secondary |
Heart rate |
ECG - tested at rest and during rhythmic handgrip exercise with and without lower body negative pressure |
Immediately after active and control interventions (IPC only) |
|
Secondary |
Heart rate |
ECG - tested at rest and during rhythmic handgrip exercise with and without lower body negative pressure |
1 hour after active and control interventions (Diet intervention only) |
|
Secondary |
Heart rate |
ECG - tested at rest and during rhythmic handgrip exercise with and without lower body negative pressure |
2 hours after active and control interventions (Diet intervention only) |
|
Secondary |
Heart rate |
ECG - tested at rest and during rhythmic handgrip exercise with and without lower body negative pressure |
3 hours after active and control interventions (Diet intervention only) |
|