Very Low Carbohydrate Diet Effects to GPS, Serum Lactate and TNF Alpha on Colorectal Cancer

Diet Modification Clinical Trial

Official title: Effect of Very Low Carbohydrate Diet to Glasgow Prognostic Score, Serum Lactate and TNF Alpha on Colorectal Cancer Patients With Best Supportive Care

Status Not yet recruiting

Clinical Trial Summary

This study examine the effects of very low carbohydrate diet (in which the calories requirements are mostly from fat) to the level of systemic inflammation (measured by Glasgow Prognostic Score), serum lactate and TNF Alpha levels

Clinical Trial Description

This study examine the effects of very low carbohydrate diet (in which the calories requirements are mostly from fat) to the level of systemic inflammation (measured by Glasgow Prognostic Score), serum lactate and TNF Alpha levels. The subjects are colorectal adenocarcinoma patients who were decided by experts to be managed by best supportive care. These patients are not deemed to be suitable for surgical intervention , chemotherapy or radiotherapy anymore. The main treatment is supportive. We would like to examined the effect of very low carbohydrate diet on these patients, in which theoretically tumtor cells of the colorectal adenocarcinoma needed glucose to replicate and increases the systemic inflammation response. ;

Related Conditions & MeSH terms

• Adenocarcinoma
• Colorectal Adenocarcinoma
• Colorectal Neoplasms
• Diet Modification
• Inflammation
• Lactate
• Systemic Inflammation
• TNF Alpha

• NCT number: NCT03221920
• Study type: Interventional
• Source: Dr. Soetomo General Hospital
• Contact: Vicky S Budipramana, PhD
• Phone: 0811315812
• Email: vickysbudi@gmail.com
• Status: Not yet recruiting
• Phase: N/A
• Start date: August 5, 2017
• Completion date: August 30, 2017