Antimicrobial-free Production of Beef Cattle's Affect on Gut Microbiome — S54  

Diet Modification Clinical Trial

Official title: Does Antimicrobial-free Production of Beef Cattle Reduce Foodborne Transmission of Resistant Bacteria to Human Consumers?

Status Completed

Clinical Trial Summary

The primary purpose of this study is to assess whether consuming foods from animals raised with antimicrobial medications influences gut health in adults between the ages of 21-69 years old. Antimicrobial medications are commonly used to help animals avoid infections while growing.

Clinical Trial Description

The researchers plan to investigate differences in the resistome (i.e., populations of antimicrobial resistance genes) and microbiome (populations of bacteria) in feces obtained from people when they consume diets containing beef derived from cattle raised conventionally (i.e. using antimicrobial drugs(AMDs)) vs. those produced in raised without antibiotics (RWA) systems. In addition, the researchers will investigate whether specific antimicrobial resistant (AMR) genes are transmitted from food to people. The hypothesis is that beef is not a significant source of resistant bacteria, and there is no difference in the likelihood of gut colonization with resistant bacteria in people eating beef derived from cattle raised conventionally (i.e. using AMDs) vs. those eating beef produced in RWA systems. ;

Related Conditions & MeSH terms

• Diet Modification

• NCT number: NCT04023604
• Study type: Interventional
• Source: Purdue University
• Status: Completed
• Phase: N/A
• Start date: January 4, 2021
• Completion date: March 4, 2022