Clinical Trials Logo

Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT04840381
Other study ID # CenTEnari
Secondary ID
Status Completed
Phase
First received
Last updated
Start date January 1, 2019
Est. completion date March 31, 2023

Study information

Verified date November 2023
Source University of Teramo
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The "CenTEnari" study is a cross-sectional study aiming at suveying the dietary and lifestyle habits of nonagenarians and centenarianss of citizens of the Abruzzo region, Italy.


Description:

Several epidemiological studies indicates that diet and physical activity are two pivotal pillars for the maintenance the of the health status and for longevity. These two last factors seem to be strictly linked between them, as demonstrated by some studies on the so called "Blue zones", particular lands in the planet where longevity rate - in terms of nonagenarians and centenarians - is particularly high. In these studies, it has been pointed out that, other than genetics, individuals following dietary regimens with lower consumption of available carbohydrates and processed foods, higher consumption of fruit, vegetables, cereals and pulses and moderate intake of meat, fish and dairy foods live longer and in a healthier status. The Abruzzo region is characterized by a great gastronomical variability, due also to the particular geographical characterization, with a few kilometer distance between sea and mountains. However, most of these dietary habits tend to stick in a valuable way to Mediterranean Diet, a dietary regimen listed in 2010 in the Representative List of the Intangible Cultural Heritage of Humanity by UNESCO. Intriguingly, the Mediterranean Diet is based on the intake of the above mentioned food groups, plus a recognized key role of the physical activity and conviviality in the meal consumption. Particularly, in the internal and mountainous part of the Abruzzo region, it has been found that the local citizens followed/follows a typical "dietary practice" called "sdijuno", which in local dialect means "to break the fasting of the night". In fact, "sdijuno" was the first abundant meal of the day - usually at mid-morning, based on the local vegetable-based foods - following the previous frugal dinner and breakfast meals. Thus, it can be hypothesized of 14-16 hours of almost fasting period. This evidence falls into the most recent findings showing the importance to consume meals in the middle part of the day and limiting the caloric intake during evening time, when metabolism tends to decrease according to body circadian rhythm. Based on these premises, the aim of the present study is to survey the dietary habits of nonagenarians and centenarians of the Abruzzo region - particularly focusing on their adherence to "sdijuno" practice - as well as physical activity and to collect personal data and health status information. Then, it will be investigated whether the adherence to the "sdijuno" dietary practice is relevant among the nonagenarians and centenarians and there is a link between this practice and the longevity of the volunteers. To do this, an ad hoc questionnaire has been set-up and will be administered to register food frequency and meal time, main recipes, physical activity habits, health status.


Recruitment information / eligibility

Status Completed
Enrollment 200
Est. completion date March 31, 2023
Est. primary completion date March 1, 2021
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 90 Years and older
Eligibility Inclusion Criteria: - Age = 90 years old - Borned and living for most of their life in the Abruzzo region. Exclusion Criteria: - Age lower 80 years old.

Study Design


Related Conditions & MeSH terms


Intervention

Behavioral:
Questionnaire administrations
Administration of an ad hoc questionnaire to register food frequency consumption and meal time, main recipes; phisical activity questionnaire and list of questions concerning the previous and actual health status of participants

Locations

Country Name City State
Italy University of Teramo - Faculty of Bioscience and Agro-Food and Environmental Technology Teramo

Sponsors (2)

Lead Sponsor Collaborator
University of Teramo DAngelino

Country where clinical trial is conducted

Italy, 

References & Publications (4)

Angelino D, Godos J, Ghelfi F, Tieri M, Titta L, Lafranconi A, Marventano S, Alonzo E, Gambera A, Sciacca S, Buscemi S, Ray S, Galvano F, Del Rio D, Grosso G. Fruit and vegetable consumption and health outcomes: an umbrella review of observational studies. Int J Food Sci Nutr. 2019 Sep;70(6):652-667. doi: 10.1080/09637486.2019.1571021. Epub 2019 Feb 15. — View Citation

Gensous N, Franceschi C, Santoro A, Milazzo M, Garagnani P, Bacalini MG. The Impact of Caloric Restriction on the Epigenetic Signatures of Aging. Int J Mol Sci. 2019 Apr 24;20(8):2022. doi: 10.3390/ijms20082022. — View Citation

Magrone T, Perez de Heredia F, Jirillo E, Morabito G, Marcos A, Serafini M. Functional foods and nutraceuticals as therapeutic tools for the treatment of diet-related diseases. Can J Physiol Pharmacol. 2013 Jun;91(6):387-96. doi: 10.1139/cjpp-2012-0307. Epub 2013 Apr 12. — View Citation

Poulain M, Pes GM, Grasland C, Carru C, Ferrucci L, Baggio G, Franceschi C, Deiana L. Identification of a geographic area characterized by extreme longevity in the Sardinia island: the AKEA study. Exp Gerontol. 2004 Sep;39(9):1423-9. doi: 10.1016/j.exger.2004.06.016. — View Citation

Outcome

Type Measure Description Time frame Safety issue
Primary Frequency of intake of food groups Observed information regarding the frequency of the consumption different food groups during subejects' period of youth 1 year
Secondary Moderate or Vigorous Physical Activity Per Week Self reported practice of moderate or vigorous physical activity per week during subejects' period of youth and old age (minutes-per-week) 1 Week
Secondary Mealtime Self reported information regarding the daily mealtime during subejects' period of youth and old age (hour and minutes of meal eating) 1 Day
Secondary Body weight Self reported body weight (kg) 1 Day
Secondary Body height Self reported body height (m) 1 Day
Secondary Body Mass Index (BMI) Weight and height will be combined to report BMI in kg/m^2 1 Day
See also
  Status Clinical Trial Phase
Active, not recruiting NCT04420936 - Pragmatic Research in Healthcare Settings to Improve Diabetes and Obesity Prevention and Care for Our Program N/A
Completed NCT04025099 - Internal Cues Versus External Cues for Eating and Activity N/A
Completed NCT04766528 - Effect of Diet on the Microbiota / Endoccanabinoidome Axis in Response to Physical Activity N/A
Completed NCT03277040 - Diet, Eating, and Lifestyle Improvement for Valued Employees and Their Relatives N/A
Active, not recruiting NCT05544461 - Piloting a Web-based Personalised Nutrition App (eNutri) With UK University Students N/A
Active, not recruiting NCT04748835 - The SEEA (SCI Energy Expenditure and Activity) Study
Active, not recruiting NCT04991142 - Models of Nutrition From Continuous Glucose Monitors
Recruiting NCT04487015 - A Digital Approach to Improving Carbohydrate Periodisation Behaviours in Athlete: SMART+ Study N/A
Completed NCT03748056 - Targeted Food Incentives to Improve Diet Quality and Health Among Adults N/A
Not yet recruiting NCT05960396 - Exploring the Mechanism of Dietary Pattern Improving MAFLD N/A
Enrolling by invitation NCT04314882 - The Danish National Survey of Diet and Physical Activity 2021-2023
Terminated NCT04677322 - TO ASSESS THE EFFECTIVENESS OF THE INTERVENTION OF THE LOW-SODIUM DIET IN PATIENTS WITH HTA
Completed NCT03855098 - Biomarkers of Food Intake Using a Cross-over Feeding Study N/A
Completed NCT03124446 - Mindfulness-Based College: Stage 1 N/A
Completed NCT03993652 - Kids FIRST: Family-based Intervention to Reduce Snacking and Screen Time in Children N/A
Completed NCT04766034 - Impact of Behavioral Economic Strategies on Low-Income Older Adults' Food Choices in Online Retail Settings N/A
Completed NCT03913871 - Text Message Program to Improve Eating Behaviors Among African Americans in New Orleans N/A
Completed NCT03698123 - Performance Nutrition for Residents and Fellows N/A
Completed NCT03941392 - Nutritional Study in Spanish Pediatric Population
Completed NCT03400566 - Effects of Experiential Learning on Vegetable Intake in Preschool Children N/A