Diagnostic Clinical Trial
Official title:
Role of Inflammatory Markers Measured Using Flow Cytometry in the Diagnosis and Prognosis of Sepsis in Surgical Cancer Patients
A diagnostic and prognostic study, in which the expression of CD64 in activated neutrophils and CD64 and IL17A regulatory T cells in patients with sepsis will be evaluated as a probable marker for sepsis as a primary objective
| Status | Recruiting |
| Enrollment | 60 |
| Est. completion date | August 2024 |
| Est. primary completion date | July 2024 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 18 Years to 65 Years |
| Eligibility | Inclusion Criteria: - Cancer patients admitted to the surgical ICU following cancer related surgeries and diagnosed with sepsis Exclusion Criteria: - Refusal of patient or patient guardian to participate. - Intraoperative massive blood loss and massive blood transfusion - Patients with impaired preoperative kidney or liver function tests |
| Country | Name | City | State |
|---|---|---|---|
| Egypt | Walaa Y Elsabeeny | Cairo |
| Lead Sponsor | Collaborator |
|---|---|
| National Cancer Institute, Egypt |
Egypt,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | To evaluate the expression CD4 | Serology | 7 days | |
| Primary | To evaluate the expression CD25 | Serology | 7 days | |
| Primary | To evaluate the expression IL17 | Serology | 7 days |
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