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Diabetic Retinopathy clinical trials

View clinical trials related to Diabetic Retinopathy.

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NCT ID: NCT02390245 Completed - Cataract Clinical Trials

Philadelphia Telemedicine Glaucoma Detection and Follow-Up Study

Start date: September 2014
Phase: N/A
Study type: Interventional

The goal is to conduct a 5-year prospective, randomized controlled trial to test an innovative, community-based intervention using posterior and anterior fundus photography of the optic nerve and macula and intraocular eye pressure measurements to improve access and utilization of eye care to detect, treat, and manage high-risk patients with previously undiagnosed glaucoma and other eye diseases. Research shows that subject failure to attend follow-up eye care appointments diminishes any previous benefits of community screenings for glaucoma. Greater adherence to follow-up visits can reduce glaucomatous blindness.

NCT ID: NCT02388984 Active, not recruiting - Clinical trials for Non-proliferative Diabetic Retinopathy

Phase III Study of Compound Danshen Dripping Pills to Treat Diabetic Retinopathy

Start date: May 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of Compound Danshen Dripping Pills in patients with diabetic retinopathy(Syndrome Of Qi-Stagnation and Blood Stasis).

NCT ID: NCT02366468 Completed - Clinical trials for Diabetic Retinopathy

Study of Efficacy of Ranibizumab in Different Regimens in Patients With Diabetic Macula Edema

DIVERSE
Start date: February 23, 2015
Phase: Phase 4
Study type: Interventional

The purpose of this study was to demonstrate that the change of best corrected visual acuity (BCVA) was comparable in patients treated with ranibizumab at the discretion of the investigator vs. treatment according to a standard of care scheme (pro re nata, as needed).

NCT ID: NCT02353923 Active, not recruiting - Clinical trials for Diabetic Retinopathy

OcuStem Nutritional Supplement in Diabetic Patients With Mild to Moderate Non-proliferative Retinopathy

Start date: September 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether supplementation with OcuStem, a nutritional supplement, will reduce the progression of mild to moderate diabetic retinopathy.

NCT ID: NCT02349516 Withdrawn - Clinical trials for Diabetic Retinopathy

Squalamine Lactate Eye Drops in Combination With Ranibizumab in Patients With Diabetic Macular Edema (DME)

Start date: February 2015
Phase: Phase 2
Study type: Interventional

A randomized, controlled study of the safety and efficacy of Squalamine Lactate Eye Drops in combination with Ranibizumab intravitreal injections in patients with diabetic macular edema. The study duration is 52 weeks and patients will be randomized to one of four treatment arms.

NCT ID: NCT02339909 Completed - Diabetes Clinical Trials

Incentives in Diabetic Eye Assessment by Screening

IDEAS
Start date: March 2015
Phase: N/A
Study type: Interventional

This trial is a randomised controlled trial to assess whether annual attendance rates at diabetic eye screening appointments in Kensington, Chelsea and Westminster could be improved by offering invitees a small financial incentive. The research questions are: 1. Are incentives an effective strategy to encourage participation in the screening programme? 2. Does the design of the financial incentive scheme affect its effectiveness in influencing participation in health screening? 3. Does the choice of incentive scheme, if successful, attract patients who have a different demographic or socioeconomic status to those who attend screening regularly? 4. Is offering these incentives a cost-effective strategy for enhancing participation?

NCT ID: NCT02337972 Recruiting - Clinical trials for Diabetic Retinopathy

Conjunctival Flora Patterns After Serial Intravitreal Injections in Diabetic Patients

Start date: January 2015
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the conjunctival bacterial flora and antibiotic resistance patterns following serial intravitreal injections of anti-VEGF in diabetic patients, using a povidone-iodine preparation without preinjection or postinjection topical antibiotics.

NCT ID: NCT02334137 Completed - Clinical trials for Diabetic Retinopathy

A Pilot Project to Assess the Impact of Diabetes Education During Ophthalmology Visits

LionsDMed
Start date: November 2014
Phase: N/A
Study type: Observational

The overarching purpose of this project is to provide diabetes education to the diverse patient population at the Lions Eye Clinic, a resident-run ophthalmology practice at California Pacific Medical Center. Because of high clinic volume in a teaching environment, our patients often experience long wait times. The goal of this program is to utilize this wait time for diabetes education, a much-needed corollary to the eye care that patients receive at our clinic. This pilot project will investigate the impact of a program like this in our patient population. Specifically, the investigators are investigating whether diabetes education delivered in an ophthalmology setting enhances patient understanding of diabetes (via knowledge surveys) and/or leads to improved blood glucose control (via hemoglobin A1c). This is a 6-month study that runs through April 2015, and looks at the impact of an interactive diabetes education iPad app +/- in-person sessions with a diabetes educator. A subset of patients who meet with a diabetes educator will also be shown their own retinal images (compared to a normal retina).

NCT ID: NCT02330042 Active, not recruiting - Clinical trials for Diabetic Retinopathy

OCT Biomarkers for Diabetic Retinopathy

Start date: September 2014
Phase:
Study type: Observational

Diabetic retinopathy (DR) is caused by changes in the blood vessels of the retina associated with long-term Type 1 or Type 2 diabetes mellitus. DR is a leading cause of blindness in the United States. Standard optical coherence tomography (OCT) cannot directly detect vascular changes, which may occur early affecting the passage of blood through the tiny capillaries (reduced capillary flow) or cause the greatest damage through formation of abnormal blood vessel growth (neovascularization). Currently, fluorescein angiography (FA) is the gold standard for detecting these changes, but FA requires an injection of a dye into the vein of the arm of the patient. This dye can cause undesirable side effects. Recently, OCT has been used to make functional measurements (such as total retinal blood flow among others) and to perform angiography. Thus, functional OCT may provide a useful, alternate way to evaluate diabetic retinopathy.

NCT ID: NCT02328118 Recruiting - Clinical trials for Proliferative Diabetic Retinopathy

25-Gauge Vitrectomy With Ranibizumab or Triamcinolone Acetonide on Proliferative Diabetic Retinopathy in China

RaTAPDR
Start date: February 2015
Phase: Phase 2/Phase 3
Study type: Interventional

Proliferative diabetic retinopathy(PDR) is the leading cause of visual loss in diabetic patients. Operation is an efficient method to treat PDR. Anti-vascular endothelial growth factor (anti-VEGF) can be used as an adjuvant therapy which can make operation more easy.