Nephropathy In Type 2 Diabetes and Cardio-renal Events — NID-2  

Diabetic Nephropathy Clinical Trial

Official title: Nephropathy in Type 2 Diabetes: Effects of an Intensive Multifactorial Intervention Trial on Cardio-renal Events.

Status Completed

Clinical Trial Summary

The NID-2 study, a multicentric study (21 centres enrolled), was planned in two phases:

Phase 1(observational study, completed in September 2005): after the identification of a type-2 diabetic population with typical Diabetic Nephropathy (DN), to study of the rate of renal and cardiovascular events during a middle term follow-up.

Phase 2(interventional study, started in October 2005): after randomization in two groups, a group (intervention group) is treated with an intensive multifactorial intervention whose aim is to reduce morbidity and mortality due to diabetic complications. The other group (control group) continues the conventional therapy . To avoid bias in the treatment in each center, the randomization was performed for centre.

Clinical Trial Description

The same patients that completed the first phase of the NID-2 study (observation) were enrolled for the phase 2 of the study (intervention). ;

Related Conditions & MeSH terms

• Diabetes Mellitus, Type 2
• Diabetic Nephropathies
• Diabetic Nephropathy
• Kidney Diseases

• NCT number: NCT00535925
• Study type: Interventional
• Source: University of Campania "Luigi Vanvitelli"
• Status: Completed
• Phase: Phase 4
• Start date: October 2005
• Completion date: May 2019