Diabetic Macular Ischemia Clinical Trial
Official title:
Evaluation of the Effects of Oxygen Therapy and Enalapril for Diabetic Macular Ischemia
| NCT number | NCT00899587 |
| Other study ID # | 8753 |
| Secondary ID | |
| Status | Recruiting |
| Phase | Phase 1 |
| First received | May 11, 2009 |
| Last updated | May 11, 2009 |
In this study, patients were divided into 3 group with 35 cases including: 1.oxygen
2.enalapril 3.control.
In the beginning of the study, best corrected visual acuity (BCVA), uncorrected visual
acuity (UCVA), and optical coherence tomography (OCT) were measured. Patients in the oxygen
group were given oxygen 10 lit/min 1 hour twice a day at the first month, once a day at the
second month and every other day at the third month. In the enalapril group, patients were
given enalapril 5 mg every night and placebo was given for the patients in third group. At
the end of first month the patients' vision was checked again and at the the end of the
third month the first physical examinations were performed. In the first group, arterial
blood gas (ABG) was taken before and after oxygen therapy as well.
| Status | Recruiting |
| Enrollment | 0 |
| Est. completion date | |
| Est. primary completion date | |
| Accepts healthy volunteers | |
| Gender | Both |
| Age group | N/A and older |
| Eligibility |
Inclusion Criteria: - Patients diagnosed with diabetic macular ischemia Exclusion Criteria: - HTN > 1140/90 or HTN controlled by ACE inhibitors - FBS > 200 - Severe anemia, COPD, cataract, HRPDR and diffuse macular edema |
N/A
| Country | Name | City | State |
|---|---|---|---|
| Iran, Islamic Republic of | Ophthalmic Research Center | Tehran |
| Lead Sponsor | Collaborator |
|---|---|
| hahid Beheshti University of Medical Sciences |
Iran, Islamic Republic of,