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Diabetic Foot clinical trials

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NCT ID: NCT01729286 Terminated - Clinical trials for Foot Ulcer, Diabetic

Health Economic Assessment of Lower Extremity Diabetic (HEALED) Ulcers With PriMatrix

HEALED
Start date: September 2012
Phase: N/A
Study type: Interventional

The objective of this study is to compare the effectiveness of PriMatrix Moist Wound Therapy (MWT) with Standard of Care MWT for the treatment of chronic diabetic foot ulcers in subjects with diabetes mellitus and without significantly compromised arterial circulation.

NCT ID: NCT01717183 Recruiting - Clinical trials for Diabetic Foot Ulcer(s)

Assessment of the Efficacy and Safety of a New Wound Dressing in the Local Treatment of Diabetic Foot Ulcers

Start date: April 2013
Phase: N/A
Study type: Interventional

The main purpose of this trial is to demonstrate that the new dressing is more effective than the current dressing in the local treatment of chronic foot ulcers in diabetic patients.

NCT ID: NCT01710774 Active, not recruiting - Diabetic Foot Clinical Trials

Telemedicine Follow-up in Primary Health Care for Diabetes-related Foot Ulcers

DiaFOTo
Start date: April 2012
Phase: N/A
Study type: Interventional

This study will investigate whether telemedicine follow-up care for people with diabetes-related foot ulcers and people with leg ulcers (without diabetes) in municipal primary health care in collaboration with specialist health care is an equivalent alternative to traditional outpatient clinical follow-up in specialist health care (noninferiority trial) in relation to healing time.

NCT ID: NCT01710553 Completed - Diabetic Foot Clinical Trials

BE STUDY OF METFORMIN GSK 1000mg

BA/BE 199/11
Start date: July 2012
Phase: Phase 2
Study type: Interventional

A randomized, balanced, open label, crossover, two period, two treatment, two sequence, single dose, oral bioequivalence study under fasting condition. It is a pivotal study to demonstrate the bioequivalence of Metformin 1000 mg tablets manufactured by Savipharm J.S.C, Vietnam and Glucophage® 1000 mg tablets of Merck Sante, France in healthy adult human male subjects under fasting condition

NCT ID: NCT01710540 Completed - Diabetic Foot Clinical Trials

BE Study of Metformin GSK 850mg

BA/BE 198/11
Start date: August 2012
Phase: Phase 2
Study type: Interventional

A randomized, balanced, open label, crossover, two period, two treatment, two sequence, single dose, oral bioequivalence study under fasting condition. It is a pivotal study to demonstrate the bioequivalence of Metformin 850 mg tablets manufactured by Savipharm J.S.C, Vietnam and Glucophage® 850 mg tablets of Merck Sante, France, in healthy adult human male subjects under fasting condition.

NCT ID: NCT01710527 Completed - Diabetic Foot Clinical Trials

BE Study of Metformin GSK 500mg

BA/BE 173/11
Start date: May 9, 2012
Phase: Phase 2
Study type: Interventional

A randomized, balanced, open label, crossover, two period, two treatment, two sequence, single dose, oral bioequivalence study under fasting condition. It is a pivotal study. To demonstrate the bioequivalence of Metformin 500 mg tablets manufactured by Savipharm J.S.C, Vietnam and Glucophage® 500 mg tablets of MERCK SANTE in healthy adult human male subjects under fasting condition and to monitor the safety of the study subjects.

NCT ID: NCT01699100 Completed - Clinical trials for Foot Ulcer, Diabetic

Reduction of Plantar Pressure in Neuropathic Diabetic Foot Patients Using Insoles With Removable Pegs Design

Start date: September 2011
Phase: N/A
Study type: Interventional

The purpose of this study was to determine if insoles with removable pegs could effectively reduce the plantar aspect pressure with the aid of in-shoe plantar pressure analysis for guidance of peg removal.

NCT ID: NCT01693133 Completed - Diabetic Foot Ulcer Clinical Trials

Trial of Dehydrated Human Amnion/Chorion Membrane (dHACM) In the Management of Diabetic Foot Ulcers

Start date: July 2012
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the percentage of patients with complete diabetic foot ulcer (DFU) closure following up to 12 weeks of treatment with either dehydrated human amnion/chorion membrane (dHACM) plus standard of care (SOC) or SOC alone.

NCT ID: NCT01686139 Not yet recruiting - Clinical trials for Type II Diabetes Mellitus With Ulcer

Safety Study of Stem Cells Treatment in Diabetic Foot Ulcers

Start date: March 2016
Phase: Phase 1
Study type: Interventional

Diabetes Mellitus (DM) can be regarded as one of the "epidemics" of the western world. DM contributes to severe morbidity and mortality due to damage in the target organs (neuropathy, vasculopathy, nephropathy, retinopathy). It affects the quality of life of the patients because of increased rate of blindness, IHD, stroke, end stage renal failure, hemodialysis and lower limb amputations (LLA).The Diabetic Foot (DF) is defined as destruction or infection of tissue/s in the foot of diabetic patients due to neurological damage and / or different levels of Peripheral Vascular Disease (PVD). Diabetic foot complications are the most common cause of lower extremity amputations in the industrialized world. The lifetime occurence of Diabetic Foot Ulcers (DFU) is 20% in diabetic patients. Between 15% - 25% of the foot ulcers will lead to lower limb amputations. It has been shown that Mesenchymal Stem Cells (MSCs) could be an effective therapy for many diseases including acute respiratory distress syndrome, spinal cord injury, liver injury and critical limb ischemia. Stem cells can be obtained from either the patient (autologous) or non-related healthy donors (allogeneic). The purpose of this study is to determine the safety and efficacy of cultured Bone Marrow Mesenchymal Stromal Cells (BM-MSCs) from allogeneic donors for treatment of chronic leg wounds of diabetic patients.

NCT ID: NCT01681160 Completed - Clinical trials for DIABETIC FOOT ULCERS

Study of Maggot Therapy in Diabetic Foot Ulcers

MDT
Start date: January 2009
Phase: N/A
Study type: Interventional

This study was a Kind of clinical trial with equal randomization, that have been done from January 2009 to June 2011 in the AFZALIPOOR hospital endocrine ward in Kerman-Iran on 128 diabetic patient who had foot wounds.Replacement of conventional therapy by new methodes is one of the more important aims for health professional specially for nurses.One of this new treatment is maggot therapy.