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Diabetic Foot clinical trials

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NCT ID: NCT01912092 Completed - Clinical trials for Diabetic Foot Ulcer (DFU)

Askina Calgitrol Paste Diabetic Foot Ulcers

Start date: April 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the efficacy of Askina® Calgitrol® Paste in reducing local infection in subjects treated for mildly infected Diabetic Foot Ulcers (DFU) with Askina® Calgitrol® Paste.

NCT ID: NCT01909908 Terminated - Clinical trials for Foot Ulcer, Diabetic

ECM and Blood Components for Wound Healing

Start date: February 2013
Phase: N/A
Study type: Interventional

The Extracellular Matrix (ECM) and Blood Components for Wound Healing feasibility study is a clinical trial approved by Health Canada to study the safety of extracellular matrix (ECM) and autologous blood products in wound healing.

NCT ID: NCT01903044 Active, not recruiting - Diabetic Foot Clinical Trials

Safety and Efficacy of Autologous Bone Marrow Stem Cells for Lower Extremity Ischemia Treating

Start date: September 2014
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine whether autologous bone marrow-derived stem cells are effective in the treatment of lower extremity ischemia.

NCT ID: NCT01898923 Completed - Diabetic Foot Clinical Trials

Evaluate the Efficacy and Safety of ON101 Cream for the Treatment of Chronic Diabetic Foot Ulcers

Start date: November 23, 2012
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to evaluate the efficacy of the new treatment of WH-1 ointment compared to Aquacel® Hydrofiber® dressing, applied to chronic diabetic foot ulcers for up to 16 weeks.An additional objective of this study is to collect safety information including adverse events and clinical laboratory abnormalities.

NCT ID: NCT01859117 Completed - Clinical trials for Peripheral Arterial Disease

Study of Human Placenta-derived Cells (PDA002) to Evaluate the Safety and Effectiveness in Subjects With PAD and DFU

Start date: May 2013
Phase: Phase 1
Study type: Interventional

This clinical study is being conducted to assess the safety and determine the maximum tolerated dose (MTD) of PDA-002 [human placenta-derived cells] administered into the lower leg muscles of subjects with peripheral arterial disease and diabetic foot ulcers. It will look to see if PDA-002 helps reduce some of the symptoms of PAD and/or improves ulcer healing. This study will also help to find the best dose of PDA-002 to use in future studies.

NCT ID: NCT01858545 Terminated - Clinical trials for Foot Ulcer, Diabetic

A Comparative Efficacy Study: Treatment for Non-healing Diabetic Foot Ulcers

Start date: May 2013
Phase: N/A
Study type: Interventional

The primary objective of this study is to assess the effectiveness of MatriStem devices compared to cellular dermal replacement tissue, for the treatment of non-healing diabetic foot ulcers.

NCT ID: NCT01849965 Terminated - Clinical trials for Diabetic Foot Ulcers

Phase 3 Study Evaluating Efficacy and Safety of DSC127 Compared With Vehicle and With Standard-of-care in Diabetic Foot Ulcers

STRIDE 2
Start date: April 2013
Phase: Phase 3
Study type: Interventional

To determine if aclerastide (DSC127) is effective in increasing incidence of complete wound closure up to 10 weeks confirmed 2 weeks later, compared with vehicle (gel without active ingredient) and compared with a standard-of-care gel, in subjects with diabetes mellitus (DM) who have chronic Wagner Grade 1 or 2 diabetic foot ulcers, 0.75 - 6cm2 in size.

NCT ID: NCT01844479 Completed - Diabetic Foot Ulcer Clinical Trials

Multi-layer Insoles for a Patient-specific Approach to Shear and Pressure Reduction in Diabetes-related Foot Ulcer

Start date: December 2012
Phase: N/A
Study type: Interventional

In this pilot study, the first objective is to bench test a novel shear reducing insole and compare it to current standard insoles and shoes. The second objective is to study twenty-seven insensate diabetes patients with pre-ulcerative foot callus to examine for changes in spatial temporal gait including gait initiation, risk of falling, static and dynamic balance, and plantar temperature response to walking and consecutive plantar stress in both footwear conditions.

NCT ID: NCT01840085 Terminated - Diabetic Foot Ulcer Clinical Trials

Open-Label Study in Diabetic Foot Ulcers (DFU), to Evaluate Safety of 0.03% DSC127 Topical Gel in Chronic Use

STRIDE 5
Start date: December 2015
Phase: Phase 3
Study type: Interventional

To evaluate the safety of topical 0.03% DSC127 Gel when used for one or more continuous treatment periods on a chronic Wagner Grade 1 or 2 foot ulcer(target ulcer) or multiple ulcers in diabetic subjects. The maximum duration of any treatment period is 24 weeks.

NCT ID: NCT01835379 Completed - Diabetic Foot Ulcer Clinical Trials

Study of Oasis Ultra in Diabetic Foot Ulcers

Start date: May 2013
Phase: Phase 4
Study type: Interventional

Many people with diabetes will develop a non-healing diabetic foot ulcer. Many ways are available to try to get a diabetic foot ulcer to heal, including application of Oasis Ultra. The hypothesis to be tested is that application of Oasis Ultra will cause more diabetic foot ulcers to heal than wounds treated with regular medical care. Subjects will have their diabetic foot wounds treated for up to 12 weeks with Oasis Ultra or regular medical care .