Reversing Diabetic Peripheral Neuropathy Through Exercise

Status Completed

Clinical Trial Summary

This project proposes a longitudinal design that uses multinuclear-MRI to evaluate the mechanistic effects of exercise on skeletal muscle function and peripheral nerve integrity in patients with diabetic peripheral neuropathy (DPN), and to determine whether exercise can reverse DPN symptoms. The investigators will prescribe a 10-week exercise program to 40 DPN patients. The investigators will acquire multinuclear-MRI data before and after the intervention that can provide mechanistic insight into the adaptations in lower leg muscle function and peripheral nerve integrity of patients with DPN, and their role in improving DPN symptoms following physical exercise intervention.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Diabetes
Peripheral Nervous System Diseases
Peripheral Neuropathy

Clinical Trial Details

NCT number	NCT03686423
Study type	Interventional
Source	NYU Langone Health
Contact
Status	Completed
Phase	N/A
Start date	November 28, 2018
Completion date	June 30, 2022

View Details

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