Effects of Prebiotics on GLP-1 in Type 2 Diabetes

Status Completed

Clinical Trial Summary

The aim of the study is to compare the effects of prebiotics versus placebo on blood concentrations of glucagon-like peptide-1 in subjects with diabetes type 2.

Clinical Trial Description

We looked at 6 weeks supplementation with a prebiotic fibre mix of inulin and FOS. Cross over design compared to maltodextrin as placebo. Additional outcome measures: blood glucose, insulin, GLP-2, ghrelin, PYY and leptin after a standardized mixed meal test. Also measured changes in microbiota composition and SCFA in feces before and after intervention/placebo periods, and subjective measures of appetite. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02569684
Study type	Interventional
Source	Oslo University Hospital
Contact
Status	Completed
Phase	N/A
Start date	October 2015
Completion date	December 2019

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