Clinical Trials Logo
  1. Home
  2. Diabetes Mellitus, Type 2
  3. NCT02538120
  4. Details
NCT02538120 Clinical Trial

Assessment of the Neurovascular Microcirculatory Response in Diabetes Type 1 Patients

Diabetes Mellitus Type 1 Clinical Trial

— NEURODIAB1  

Official title:
Assessment of the Neurovascular Microcirculatory Response in Diabetes Type 1

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT02538120
Other study ID # 2012-A010008-35
Secondary ID
Status Completed
Phase N/A
First received August 14, 2015
Last updated February 11, 2016
Start date May 2012
Est. completion date September 2015

Study information
Verified date August 2015
Source University Hospital, Angers
Contact n/a
Is FDA regulated No
Health authority France: Institutional Ethical Committee
Study type Interventional

Clinical Trial Summary

This study aims to see whether or not the diabetes 1 patients have a neurovascular microcirculatory dysfunction using various microvascular tests which have been previously validated.

Microvascular responses will be assessed by Laser Speckle Contrast Imaging and expressed in Laser Speckle Perfusion Units (LSPU).

Description:

The investigators will compare microvascular responses between diabetes type 1 patients with matched control-subjects.

Recruitment information / eligibility
Status Completed
Enrollment 40
Est. completion date September 2015
Est. primary completion date September 2015
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Diabetes type 1 patients

- Matched control-subjects

Exclusion Criteria:

- Patients or subjects with anti-inflammatory drugs

Study Design

Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Basic Science

Related Conditions & MeSH terms

Intervention

Other:
• Microvascular assessment
Microvascular assessment

Locations
Country Name City State
France University Hospital Angers

Sponsors (1)
Lead Sponsor Collaborator
University Hospital, Angers

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary Neurovascular microcirculatory response Neurovascular response will be assessed by laser speckle contrast imaging using various microvascular tests such as deionized water iontophoresis, local heating test. Results will be explained in Laser Speckle Perfusion Units (LSPU) one day No
See also
  Status Clinical Trial Phase
Recruiting NCT01508065 - Measuring and Monitoring Blood Glucose Levels Utilizing Non-invasive Blood Glucose Monitoring Device
Completed NCT01788033 - Effects of XOMA 052 on Insulin Production in Type 1 Diabetes Phase 2
Active, not recruiting NCT01271517 - Basal Analog Study - Comparison of Lantus or Levemir With NPH Insulin From T1DM Diagnosis Phase 4
Recruiting NCT01800734 - Mixed Meal Test in Type 1 Diabetes: Optimization of Artificial Pancreas-Pilot Study Phase 4
Recruiting NCT06088615 - Feasibility of Non-invasive Glucose Monitoring by Using Photothermal Deflectometry
Completed NCT02127047 - Effects of Exercise and Inhibition of Dipeptidyl Peptidase-4 on Insulin Secretion in Subjects With Type 1 Diabetes Phase 2
Completed NCT01689090 - Diameter Changes of Retinal Vessels During Hypoxia N/A
Completed NCT00006505 - Solitary Islet Transplantation for Type 1 Diabetes Mellitus Using Steroid Sparing Immunosuppression Phase 2
Not yet recruiting NCT06217302 - Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease Phase 3
Recruiting NCT02750111 - Continuous Glucose Monitoring During Intecorse in Young Adults With Type 1 Diabetes N/A
Recruiting NCT02545062 - MoCa Test for the Early Detection of Mild Cognitive Impairment During Annual Assessment of Young Adults With Diabetes and in a Control Group Without Diabetes N/A
Completed NCT02146651 - A Double-blinded, Randomised, Four-period Crossover Euglycemic Clamp Trial Investigating the Dose-response and Dose-exposure Relationship of BioChaperone Insulin Lispro in Three Different Doses in Subjects With Type 1 Diabetes Phase 2
Completed NCT02403375 - Comparing Continuous Subcutaneous Insulin Infusion With Multiple Daily Injections to Reach HbA1c Targets in Children and Adolescents With Type 1 Diabetes N/A
Terminated NCT00896610 - Natural History of Autoimmune Diabetes and Its Complications
Terminated NCT02701257 - The iLet Introduction Study: A Feasibility Study of the iLet, a Fully Integrated Bihormonal Bionic Pancreas N/A
Completed NCT02094534 - A Prospective, Randomized, Double-blind, Placebo Controlled Study to Assess the Impact of ORMD-0801 (Insulin Capsules) on the Exogenous Insulin Requirements of Type 1 Diabetics Phase 2
Completed NCT01334151 - Pharmacokinetic and Pharmacodynamic Properties of BIOD-105 and BIOD-107 Compared to Humalog® in Subjects With Type 1 Diabetes Phase 1
Active, not recruiting NCT02624804 - A Pilot Study of the Therapeutic Potential of Stem Cell Educator Therapy in Type 1 Diabetes Phase 1
Completed NCT02465411 - Long Term CGM Treatment in Patients With Type 1 Diabetes Treated With Insulin Injections N/A
Completed NCT02157155 - A Study of Intracellular Signaling in Muscle and Fat Cells During Ketosis N/A