Diabetes, Type 2 Clinical Trial
Official title:
Insulin Glargine vs NPH as Basal Insulin on Glycemic Values in Hospitalized Patients: The Inova Diabetes Study
The purpose of this study is to compare the safety and effectiveness of the two different basal insulins commonly used for basal blood sugar control in the treatment of type 2 diabetes mellitus in patients who are hospitalized and require low doses of insulin: neutral protamine Hagedorn (NPH) insulin and glargine (Lantus®) insulin. Previous research has shown that both NPH insulin and glargine (Lantus®) insulin is safe and effective for the control of blood sugar in a type 2 diabetic patient. This research is being done because the costs of medications for diabetic patients are very expensive. Our goal with this research is to show that a less expensive insulin (NPH) is as safe and effective as a more expensive insulin [glargine (Lantus®)] in patients with type 2 diabetes mellitus who are in the hospital.
This is a randomized, open label trial comparing effectiveness of insulin glargine and insulin NPH in a basal plus correctional regimen. Patients will be randomized to either an intervention (NPH) or a control group (glargine) upon admission. The following data will be collected: age, sex, weight, preadmission diabetes medications, admission diagnosis, HbA1C, blood glucose (BG), chemistry, hematology, urine analysis, pregnancy test, duration of hospitalization, insulin dose, and discharge status. Data will be recorded and maintained confidentially. ;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT01805414 -
Breakfast Nutrition and Inpatient Glycemia
|
N/A | |
| Completed |
NCT01427660 -
iDecide.Decido: Diabetes Medication Decision Support Study
|
N/A | |
| Completed |
NCT02648685 -
The Study to Investigate the Contribution of Basal and Postprandial Glucose to Overall Hyperglycemia in T2DM
|
||
| Completed |
NCT00141232 -
Evaluating Atorvastatin With Omega-3 Fatty Acids in Cardiovascular Risk Reduction in Patients With Type 2 Diabetes
|
Phase 4 | |
| Completed |
NCT03397225 -
A Lifestyle Intervention for Type 2 Diabetes Patients in Kuwait and Its Impact on Glycaemic Control
|
N/A | |
| Completed |
NCT01837680 -
Glycemic Control Using Insulin Levemir Versus Insulin NPH for Diabetes in Pregnancy
|
N/A | |
| Completed |
NCT01336738 -
Study Of Safety And Efficacy Of PF-04991532 In Subjects With Type 2 Diabetes Mellitus
|
Phase 2 | |
| Completed |
NCT00308737 -
Safety of Inhaled Insulin With Type 1 and Type 2 Diabetes
|
Phase 3 | |
| Completed |
NCT00246987 -
A Trial to Evaluate BMS-298585 as Monotherapy in Subjects With Type 2 Diabetes Who Have Inadequate Glycemic Control
|
Phase 3 | |
| Completed |
NCT01193179 -
A Phase 3 Study of OPC-262 in Patients With Type 2 Diabetes
|
Phase 3 | |
| Completed |
NCT00857558 -
A Phase 2 Study of OPC-262 in Patients With Type 2 Diabetes
|
Phase 2 | |
| Terminated |
NCT01350102 -
The Relationship of Hemoglobin A1c and Diabetic Wound Healing
|
Phase 4 | |
| Completed |
NCT01624116 -
Comparison of Hypoglycaemic Regimens During Ramadan Fasting in Type 2 Diabetes
|
N/A | |
| Completed |
NCT01634282 -
Along-term Study of OPC-262 in Patients With Type 2 Diabetes
|
Phase 3 | |
| Recruiting |
NCT06340854 -
A Research Study to See How Switching From a Daily Basal Insulin to a New Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine in Adults With Type 2 Diabetes
|
Phase 3 |