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Clinical Trial Summary

Intensive Insulin Therapy (IIT) may be given in Type 2 Diabetes (T2DM) in two different ways :

- as Basal/bolus therapy (B/B) in four-five injections per day .

- as Modern Premixed Insulins( MPI's) three times per day . The better diabetes control is achieved, the more likely patient would suffer from hypoglycemic episodes. We propose that the probability of hypoglycemia and its severity has no difference in two main insulin therapy schemes mentioned above.

The objective of the study is to compare the incidence of hypoglycemia and its severity in well-controlled ( HBA1C less than 7%) diabetic individuals treated by two different regimens, through analysis of data received by Continuous Glucose Monitoring (CGM, Free Style Navigator).


Clinical Trial Description

n/a


Study Design

Observational Model: Cohort, Time Perspective: Prospective


Related Conditions & MeSH terms


NCT number NCT01627509
Study type Observational
Source Sheba Medical Center
Contact Jacob Ilani, Dr.
Phone +97235303103
Email Jacob.Ilany2@sheba.health.gov.il
Status Recruiting
Phase N/A
Start date May 2012
Completion date August 2013