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NCT01437332 Clinical Trial

Molecular Mediators of Nerve Injury Signaling

Diabetes Clinical Trial

Official title:
Molecular Mediators of Nerve Injury Signaling

Clinical Trial Details — Status: Enrolling by invitation

Administrative data
NCT number NCT01437332
Other study ID # 0356-11-RMB
Secondary ID
Status Enrolling by invitation
Phase N/A
First received September 19, 2011
Last updated September 19, 2011
Start date September 2011

Study information
Verified date September 2011
Source Rambam Health Care Campus
Contact n/a
Is FDA regulated No
Health authority Israel: Israel Medical Association
Study type Observational

Clinical Trial Summary

Specific proteins and other signaling molecules are increased and decreased following nerve injury. Some of these are important in producing pain or explaining why pain persists after traumatic nerve injuries or in disease states such as diabetes. In this study, the investigators hypothesize that it is possible to detect changes in specific signaling molecules and that these will provide insights into novel treatment strategies. The patients to be included are those who are undergoing the removal of tissue during surgery. The tissues that would otherwise be discarded will be included in the study as appropriate.

Recruitment information / eligibility
Status Enrolling by invitation
Enrollment 50
Est. completion date
Est. primary completion date September 2016
Accepts healthy volunteers No
Gender Both
Age group 18 Years to 80 Years
Eligibility Inclusion Criteria:

- patients undergoing surgery where tissue removal is anticipated

Exclusion Criteria:

- age younger than 18

Study Design

Observational Model: Ecologic or Community, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
Israel Rambam Health Care Campus Haifa

Sponsors (1)
Lead Sponsor Collaborator
Rambam Health Care Campus

Country where clinical trial is conducted

Israel, 

References & Publications (1)

Ebenezer GJ, McArthur JC, Thomas D, Murinson B, Hauer P, Polydefkis M, Griffin JW. Denervation of skin in neuropathies: the sequence of axonal and Schwann cell changes in skin biopsies. Brain. 2007 Oct;130(Pt 10):2703-14. — View Citation

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