Diabetes Mellitus Clinical Trial
Official title:
Effect of Coffee Consumption on the Glycemic Index of Khalas Dates Tested in Healthy and Diabetic Subjects
The aim of this study was to evaluate the composition of Khalas, a very common type of dates used in the UAE and to determine the effects of drinking Arabic coffee on the results of GI tests in both healthy and diabetic subjects.
Background:The consumption of dates along with coffee is a deeply rooted habit in many
societies. This study was designed to determine the effect of coffee consumption on the
glycemic index of a common variety of dates (Khalas) tested in healthy subjects and
individuals with type 2 diabetes mellitus.
Methods:Composition analysis was carried out for Khalas dates (Tamer stage) and the weight of
the dates flesh equivalent to 50 g of available carbohydrate was calculated. The study
subjects were thirteen healthy volunteers with a mean (± SD) age of 40.2 ± 6.7 years and ten
participants with type 2 diabetes mellitus (controlled on lifestyle measures and/or
metformin) with a mean HbA1c (± SD) of 6.6 ± (0.7 %) and a mean age (± SD) of 40.8 ± 5.7
years. Each subject was tested on five separate days with 50 g of glucose (on 3 occasions)
and 50 g equivalent of available carbohydrates from the dates without coffee (on one
occasion) and with coffee (on another occasion). Capillary glucose was measured in the
healthy subjects at 0, 15, 30, 45, 60, 90 and 120 min and for the diabetics at 0, 30, 60, 90,
120, 150 and 180 min. The glycemic indices were determined as ratios of the incremental areas
under the response curves for the dates alone/with coffee compared to glucose. Statistical
analyses were performed using Student's t-tests.
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