Diabetes Mellitus Clinical Trial
Official title:
Molecular and Genetic Analysis of Disturbed Wound Healing in Barbadians With Diabetic Foot Ulcers
This observational study aims to identify risk factors and molecular mechanisms of impaired wound healing, to guide better foot care in the diabetic population.
Diabetes is linked with vascular complications of the eye, kidney and foot. Barbadians
suffer from an unusually high prevalence of diabetic foot complications, which can cause
difficult-to-heal foot ulcers and even lead to amputations of the toes or feet.Studies from
the CDRC have indicated alarmingly high rates of amputation and mortality due to diabetic
foot in Barbados. The goal of this study is to improve early detection of persons at risk of
the vascular complications of diabetes through non-invasive scanning and genetic
susceptibility tests.
The general hypothesis to be tested in this study is that persons with diabetes (PWD) and
non-healing foot ulcers are more likely to have a disturbed mechanism for wound-healing than
PWD without this particular complication. If the hypothesis is proven correct, this will
empower patients and physicians with the diagnostic tests to make early interventions
towards avoiding the complications of diabetes.
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Observational Model: Case Control, Time Perspective: Cross-Sectional
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