In-Hospital Hyperglycemia: Effects of Treatment on Glycemic Control and Clinical Outcome

Diabetes Clinical Trial

Official title: In-Hospital Hyperglycemia: Effects of Treatment on Glycemic Control and Clinical Outcome

Status Completed

Clinical Trial Summary

To improve glycemic control of inpatients admitted to the internal medicine wards, the researchers generated a protocol based on intensive insulin treatment for use in all inpatients with hyperglycemia.

The researchers hypothesize that intensive insulin treatment will improve the glycemic control and the outcome of hospitalized patients.

Study Information:

• All patients with a history of diabetes admitted to the internal medicine ward were enrolled in the study.

• At baseline, demographic and clinical information were obtained, including information necessary to determine the severity of the illness. Venous capillary blood glucose levels were checked 4 times a day by glucometer.

• During the pre-intervention period, patients were treated according to the common practice in the hospital without any intervention. The study team collected the baseline data on the glycemic control and treatment of patients admitted with hyperglycemia.

• During the intervention period, the study team visited the ward daily and guided the medical staff as to the use of the treatment protocol.

• During the post-intervention period, the study team collected the data without active intervention in the implementation of the protocol.

• Data was collected on the mode of treatment and glycemic control of all hyperglycemic patients throughout the study. The incidence of hypoglycemia, complications (myocardial infarction, stroke, infections), mortality, transfer to intensive care unit (ICU), length of hospitalization, and disposition at discharge were noted.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label

Related Conditions & MeSH terms

• Diabetes
• Hyperglycemia

• NCT number: NCT00302874
• Study type: Interventional
• Source: Hadassah Medical Organization
• Status: Completed
• Phase: N/A
• Start date: February 2003
• Completion date: October 2004