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Novel Therapeutics and Endothelial Dysfunction in T1DM Patients — ENDIS  

Diabetes Mellitus, Type 1 Clinical Trial

Official title:
Impact of Additional Treatment With Empagliflozin or Semaglutide on Endothelial Function and Other Clinical Parameters and Biomarkers in T1DM Patients

Clinical Trial Summary

The aim of study is impact of additional treatment with new antidiabetic drugs (semaglutide or empagliflozine) compared to control group in T1DM patients - impact on endothelial function measured by FMD and FPF, arterial stiffness - measured by PWV, inflammatory biomarkers, markers of oxidative stress and endothelial progenitor cells (CD 34+/VDRL2, CD 133+/VDRL2) and correlation with glucovariability or time in range, measured with CGM system.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05857085
Study type Interventional
Source General and Teaching Hospital Celje
Contact
Status Completed
Phase Phase 4
Start date December 15, 2021
Completion date April 20, 2023
View Details
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