Metabolomic Profiling of in Patients With type2 Diabetes

Status Completed

Clinical Trial Summary

To exam the metabolomic profiling of CSF and plasma in diabetes and establish the human CSF Metabolome Database of Type 2 DM.

Clinical Trial Description

Human cerebral spinal fluid (CSF) is known to be a rich source of small molecule biomarkers for central neurological and neurodegenerative diseases. However, the metaboloic bases of CSF in diabetes patient have not been studied. In this plan, the investigators will use analytical platforms, including nuclear magnetic resonance (NMR), liquid chromatography-mass spectrometry (LC-MS), to perform quantitative metabolomics on human CSF and blood samples and further establish the human CSF Metabolome Database of DM. This work will can supply important CSF metabolic profit information and help to facilitate a wide range of metabolomic studies on central nervous system diseases and their associations disease. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03725709
Study type	Observational
Source	Chang Gung Memorial Hospital
Contact
Status	Completed
Phase
Start date	August 1, 2016
Completion date	July 31, 2019

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