Diabete Type 2 Clinical Trial
Official title:
Impact of Changes in Muscle Secretome in the Remission of Type 2 Diabetes Mellitus Induced by Bariatric Surgery
Bariatric surgery is recognized as a therapeutic modality of type 2 diabetes. The mechanisms
of this remission of diabetes remain poorly understood.
The aim of our research is to characterize the changes in muscle secretome induced by
bariatric surgery and to determine their role in improving the insulin sensitivity of
skeletal muscle and insulin secretion by the B cell responsible for the remission of
diabetes.
Bariatric surgery is recognized as a therapeutic modality of type 2 diabetes. The mechanisms
of this remission of diabetes remain poorly understood.
The aim of our research is to characterize the changes in muscle secretome induced by
bariatric surgery and to determine their role in improving the insulin sensitivity of
skeletal muscle and insulin secretion by the B cell responsible for the remission of
diabetes.
This prospective study will be carried out in insulin-resistant diabetic patients or not in
whom blood and muscle samples will be carried out before and after bariatric surgery
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT04940962 -
Translational Study Using Human Abdominal Adipose Tissue Biopsies to Investigate the Role of Cannabinoid Receptor 1 (CB1) in Controlling Endocannabinoid and Adipokine Secretion
|
N/A | |
Completed |
NCT05359341 -
Which is Better to Start With DPP-4 Inhibitors or SGLT-2 Inhibitors in Egyptian Diabetic Patients?
|
N/A | |
Recruiting |
NCT04700813 -
Research Study for Rare Pathogenic Mutations Causing Type 2 Diabetes and Complications
|
||
Completed |
NCT05413330 -
Corticosteroid Injection Combined With Cataract Surgery in Diabetic Eyes.
|
Phase 2/Phase 3 | |
Recruiting |
NCT04927377 -
Accessible and Inclusive Diabetes Telecoaching Self-Management Program
|
N/A | |
Completed |
NCT05585268 -
Electronic Decision Support for Deprescribing in Patients on Hemodialysis
|
N/A | |
Active, not recruiting |
NCT05088616 -
Native American Diabetes Project
|
N/A | |
Not yet recruiting |
NCT03273738 -
Vascular and Metabolic Changes in Postmenopausal Diabetics
|
||
Active, not recruiting |
NCT04642911 -
Longterm Follow-up of Subjects With Diabetes 2 Type Treatment With ex Vivo Gene Therapy
|
||
Withdrawn |
NCT04283617 -
Reversibility of Brain Glucose Transport and Metabolism in T2DM: an Intervention Study
|
N/A | |
Recruiting |
NCT04769687 -
Symbiotics and Systemic Inflammation in Chronic Kidney Disease
|
Phase 2 | |
Withdrawn |
NCT06104358 -
Ph 2a Study of HU6 on Energy Metabolism, Muscle and Liver Substrate Metabolism, and Mitochondrial Function in Subjects Who Are Overweight or Obese With Type 2 Diabetes
|
Phase 2 | |
Not yet recruiting |
NCT06080802 -
The Effect of Addition of Metformin to SGLT2 In Diabetic Patients With Heart Failure With Preserved Ejection Fraction
|
Phase 2/Phase 3 | |
Recruiting |
NCT04485845 -
Metformin Versus Vildagliptin in Reducing Risk of Metabolic Syndrome Complications Progression
|
Phase 4 | |
Recruiting |
NCT05050500 -
The Effect of Dapagliflozin on the Short-term Prognosis of Patients With Acute Myocardial Infarction
|
Phase 4 | |
Completed |
NCT04115657 -
The Effect of Different Starches of Boba Pearls and Sugar Substitutes Used in Milk Tea on Glycaemia, Insulinaemia and Appetite Control (Pearl Study)
|
N/A | |
Completed |
NCT06188572 -
The Effect of Peripheral Neuropathy Symptoms on Temporomandibular Joint Functionality
|
||
Completed |
NCT04120844 -
Effectiveness of Motivational Interviewing on Improving Care for Type 2 Diabetes Mellitus Patients in China
|
N/A | |
Completed |
NCT05789706 -
Use of a Smart-phone Based Medication Adherence Platform to Improve Outcomes in Uncontrolled Non-insulin Dependent Diabetes Among Veterans
|
N/A | |
Recruiting |
NCT05776420 -
Effect of a Healthy Food Voucher on Blood Glucose Control in People With Type 2 Diabetes or Prediabetes
|
Phase 3 |