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Clinical Trial Summary

Bariatric surgery is recognized as a therapeutic modality of type 2 diabetes. The mechanisms of this remission of diabetes remain poorly understood.

The aim of our research is to characterize the changes in muscle secretome induced by bariatric surgery and to determine their role in improving the insulin sensitivity of skeletal muscle and insulin secretion by the B cell responsible for the remission of diabetes.


Clinical Trial Description

Bariatric surgery is recognized as a therapeutic modality of type 2 diabetes. The mechanisms of this remission of diabetes remain poorly understood.

The aim of our research is to characterize the changes in muscle secretome induced by bariatric surgery and to determine their role in improving the insulin sensitivity of skeletal muscle and insulin secretion by the B cell responsible for the remission of diabetes.

This prospective study will be carried out in insulin-resistant diabetic patients or not in whom blood and muscle samples will be carried out before and after bariatric surgery ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03341793
Study type Interventional
Source Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Contact Jean-Paul Thissen, MD, PhD
Phone 0032 2 7654
Email jeanpaul.thissen@uclouvain.be
Status Recruiting
Phase N/A
Start date November 14, 2017
Completion date October 1, 2021

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