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Dermatitis clinical trials

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NCT ID: NCT02324972 Completed - Atopic Dermatitis Clinical Trials

Pilot Efficacy and Safety Study of AQX-1125 in Atopic Dermatitis

KINSHIP
Start date: December 2014
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to evaluate the effect of 12 weeks of treatment with once daily administration of AQX-1125 compared to placebo on change from baseline in Total Lesion Symptom Score in subjects with mild to moderate atopic dermatitis

NCT ID: NCT02317276 Terminated - Dermatitis, Atopic Clinical Trials

A Study to Determine Serum and Skin Biopsy Biomarkers in Patients Receiving Topical Corticosteroid (TCS) and Following TCS Withdrawal

GNE-AD
Start date: December 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the differential expression of AD biomarkers in serum, plasma, and skin biopsies from both lesional and non-lesional skin in moderate to severe AD patients in the presence of TCS and after withdrawal from TCS.

NCT ID: NCT02302625 Completed - Atopic Dermatitis Clinical Trials

Cognitive Behavior Therapy for Atopic Dermatitis

Start date: November 2014
Phase: N/A
Study type: Interventional

Atopic dermatitis is an inflammatory skin disease characterized by itching, dry skin and recurrent inflammatory eczema. It is one of the most common skin diseases and is associated with reduced quality of life, functional impairment and sleep difficulties. The present study aims to investigate a new exposure-based cognitive behavioral psychological treatment for the disorder. The trial is a small scale open trial (n=25) with assessments at baseline, post-treatment and 6-month follow-up. The primary outcome is the SCORAD.

NCT ID: NCT02300701 Completed - Atopic Dermatitis Clinical Trials

Role of Anti-IgE in Severe Childhood Eczema

ADAPT
Start date: December 2014
Phase: Phase 4
Study type: Interventional

To evaluate the efficacy of anti-IgE (Omalizumab/Xolair) in children with severe eczema.

NCT ID: NCT02299206 Terminated - Diaper Rash Clinical Trials

CeraVe Cream Compared to Desitin Paste for Treating Diaper Dermatitis in Infants

Start date: December 2014
Phase: N/A
Study type: Interventional

This is a single-center, 1:1 randomized, double-blind, parallel-group, non-inferiority controlled trial to demonstrate non-inferiority of CeraVe Baby Diaper Rash Cream compared to Desitin Maximum Strength Original Paste when administered to children with diaper dermatitis who are between 3 months to 18 months of age. Parents/caregivers of subjects in both groups will administer the product with each diaper change throughout the course of the study period. Product can be applied liberally as needed. Diapers and skin cleansing interventions will stay constant throughout the treatment period. Subjects will be assessed by the study doctor, parent/caregiver will be asked about any adverse effects. Parent/caregivers will also be asked to complete a daily diary that asks about changes in their baby's diaper dermatitis, a Visual Analogue Scale severity assessment of their baby's diaper dermatitis, and observations related to product use and the baby's comfort level. Parents/caregivers will also be given a questionnaire rating the use of the study products.

NCT ID: NCT02289989 Recruiting - Atopic Dermatitis Clinical Trials

Oregano Ointment vs. Standard Treatment for Pediatric Atopic Dermatitis

Start date: November 2014
Phase: N/A
Study type: Interventional

This study is designed to evaluate and compare the efficacy of 3% oregano extract ointment prepared in aqueous solution versus 1% hydrocortisone ointment, a standard treatment, in decreasing the inflammation associated with mild to moderate atopic dermatitis. We plan to recruit 40 patients on the ages comprised between 2 and 17 years old and the study duration for each of the patient is 1 month.

NCT ID: NCT02286999 Withdrawn - Atopic Dermatitis Clinical Trials

Probiotic Supplementation in Breastfed Newborn Infants

Start date: October 2015
Phase: Phase 1
Study type: Interventional

The purpose of this study is to investigate the dose of a probiotic supplement (Bifidobacterium longum subsp. infantis) required to achieve predominant gut colonization in healthy newborn, breastfed infants. The study will also examine whether supplementation with this probiotic can reduce the chance of developing eczema and food allergies in enrolled infants.

NCT ID: NCT02286700 Recruiting - Dermatitis, Atopic Clinical Trials

Skin Effects of a Topical Amino Acid Moisturizing Cream and Desonide in Atopic Dermatitis

Start date: November 2014
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the effects of an amino acid moisturizing cream and desonide cream in reducing skin symptoms associated with AD/eczema in subjects with mild to moderate atopic dermatitis/eczema.

NCT ID: NCT02277769 Completed - Dermatitis, Atopic Clinical Trials

Study of Dupilumab (REGN668/SAR231893) Monotherapy Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis

SOLO 2
Start date: November 30, 2014
Phase: Phase 3
Study type: Interventional

This is a randomized, double-blind, placebo-controlled, parallel-group study to confirm the efficacy and safety of Dupilumab monotherapy in adults with moderate-to-severe atopic dermatitis (AD).

NCT ID: NCT02277743 Completed - Dermatitis, Atopic Clinical Trials

Study of Dupilumab Monotherapy Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis

SOLO 1
Start date: October 2014
Phase: Phase 3
Study type: Interventional

This is a randomized, double-blind, placebo-controlled, parallel group study to confirm the efficacy and safety of Dupilumab monotherapy in adults with moderate-to-severe atopic dermatitis (AD).