Systemic Therapies for Pediatric Atopic Dermatitis

Status Recruiting

Clinical Trial Summary

While many patients with atopic dermatitis (eczema) can be managed with topical creams and treatments for itch, some children have such severe, long-standing disease that they need treatment with oral medications that decrease the ability of the immune system to react. However, there is not enough information on the proper use of these medications or how well they work compared with each other. The current study looks at the response of children treated with these medications to provide this information and improve their use.

Clinical Trial Description

Severe and/or refractory cases of atopic dermatitis (AD) can require systemic immunosuppressive therapy for disease control, yet there are few studies regarding the appropriate use of these drugs for pediatric AD and even less data comparing them. The current observational study will observe the effect of these therapies on children with moderate to severe atopic dermatitis as they are treated. These drugs being observed will be cyclosporine, azathioprine, mycophenolate mofetil, and methotrexate. ;

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01447381
Study type	Observational
Source	Rady Children's Hospital, San Diego
Contact	Lori Murphy, BS, CCRP
Phone	858-576-1700
Email	lmurphy@rchsd.org
Status	Recruiting
Phase	N/A
Start date	October 2011
Completion date	July 2021

View Details

See also
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