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Dermatitis, Atopic clinical trials

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NCT ID: NCT03304470 Completed - Atopic Dermatitis Clinical Trials

A Study to Evaluate the Safety and Efficacy of ATx201 in Subjects With Moderate Atopic Dermatitis

Start date: September 25, 2017
Phase: Phase 2
Study type: Interventional

This is a Phase 2, 3-week, single-center, double-blind, randomized, two-arm, vehicle controlled study, with each individual receiving both active and vehicle treatment. Approximately 30 subjects with moderate atopic dermatitis will receive topically applied ATx201 CREAM 2% and matching vehicle once daily for 3 weeks (5 mg/cm2/day), without occlusion. ATx201 and vehicle will be applied on two separate target lesions of moderate atopic dermatitis (lesions of at least 3 × 3 cm, excluding the face, scalp, genitals, hands, and feet, ideally from the same anatomical location).

NCT ID: NCT03297502 Completed - Atopic Dermatitis Clinical Trials

Safety and Bioequivalence of Pimecrolimus Cream 1% and Elidel R in Treatment of Mild to Moderate Atopic Dermatitis

Start date: June 2016
Phase: Phase 3
Study type: Interventional

A phase 3, double-blind, randomized, parallel-group, placebo-controlled, multicenter study to evaluate the safety and bioequivalence of Par Pharmaceutical Inc.'s Pimecrolimus Cream, 1% and Reference Listed Elidel® (Pimecrolimus Cream, 1%). The study compares both active treatments to a placebo control in the treatment of mild to moderate atopic dermatitis.

NCT ID: NCT03293030 Completed - Atopic Dermatitis Clinical Trials

Immunogenetic Profiling of Dupilumab for the Treatment of Atopic Dermatitis

Start date: October 22, 2018
Phase: Phase 4
Study type: Interventional

This is a single-arm, open-label study to examine the effect of dupilumab on the immunologic and genetic environment within atopic dermatitis skin lesions.

NCT ID: NCT03270566 Recruiting - Atopic Eczema Clinical Trials

Softened Water for Eczema Prevention Pilot Trial

SOFTER
Start date: February 12, 2018
Phase: N/A
Study type: Interventional

An outcome assessor-blinded pilot randomised controlled trial of an ion-exchange water softener for the prevention of atopic eczema in neonates, with an embedded mechanistic study

NCT ID: NCT03269773 Completed - Atopic Dermatitis Clinical Trials

Safety and Efficacy of FURESTEM-AD Inj. in Patients With Moderate to Severe Chronic Atopic Dermatitis(AD)

Start date: April 25, 2018
Phase: Phase 3
Study type: Interventional

This is multi-center, randomized, double-blind, parallel, placebo-controlled phase III clinical trial to evaluate the efficacy and safety of FURESTEM-AD Inj. for moderate to severe chronic atopic dermatitis

NCT ID: NCT03268174 Completed - Clinical trials for Atopic Dermatitis Eczema

Cosmetic Study to Improve the Appearance of Skin Afflicted With Mild to Moderate Atopic Dermatitis.

Start date: May 11, 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to observe the performance of a cosmetic product, AO+Mist, on the appearance of arm skin in subjects with atopic dermatitis

NCT ID: NCT03260595 Completed - Healthy Clinical Trials

A Study of Crisaborole Ointment 2% in Adult Japanese Healthy Subjects and Adult Japanese Subjects With Mild To Moderate Atopic Dermatitis

Start date: September 13, 2017
Phase: Phase 1
Study type: Interventional

This is a Phase 1 parallel-cohort study of crisaborole ointment 2% to evaluate the skin irritation potential in adult Japanese healthy subjects in Cohort 1, and to evaluate the safety, tolerability and PK in adult Japanese subjects with mild to moderate AD in Cohort 2.

NCT ID: NCT03257644 Completed - Atopic Dermatitis Clinical Trials

A Pharmacokinetic Study of Ruxolitinib Phosphate Cream in Pediatric Subjects With Atopic Dermatitis

Start date: September 21, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability and the pharmacokinetics (PK) of topical ruxolitinib cream applied to pediatric subjects (age ≥ 2 to 17 years) with atopic dermatitis (AD).

NCT ID: NCT03257215 Suspended - Atopic Dermatitis Clinical Trials

Can Vitamin D Treatment Help Treat Moderate to Severe Atopic Dermatitis in Young Children? The D-Vex Pilot Study

D-Vex
Start date: October 16, 2017
Phase: Phase 4
Study type: Interventional

Vitamin D is known to have a regulatory influence on both the immune system and skin barrier function. Studies in paediatric populations have found an inverse association of vitamin D levels and with both prevalence and severity of atopic dermatitis (AD). Trials of vitamin D as a treatment for AD are limited in number and size. There has never been a placebo-controlled randomised controlled trial of stoss high dose versus daily standard dose for the treatment of AD. Further, no trials have explored the presence of vitamin D pathway genes and response to treatment of AD. This pilot study will be used as a reference to determine outcomes and feasibility for undertaking a larger and more in depth definitive study.

NCT ID: NCT03253666 Completed - Melanoma Clinical Trials

Nurses' Health Study and Health Professionals Follow-Up Study (Dermatological Component)

Start date: January 2017
Phase:
Study type: Observational [Patient Registry]

To determine the relationships of dietary factors with the subsequent risk of dermatological diseases (such as skin cancers and inflammatory or autoimmune dermatoses) in a cohort of female registered nurses and male health professionals.