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Electroconvulsive Therapy and Neuroradiology — ECTMRI  

Depression Clinical Trial

Official title:
Effects of ECT in Treatment of Major Depression: A Prospective Neuroradiological Study of Acute and Longitudinal Effects on Brain Structure and Function

Clinical Trial Summary

The study will apply state of the art radiology through advanced magnetic resonance imaging (MRI) techniques to investigate structural and functional brain effects of ECT.

Clinical Trial Description

As a multi-disciplinary collaboration, imaging findings will be correlated to psychiatric response parameters, neuropsychological functioning as well as neurochemical and genetic biomarkers that can elucidate the underlying mechanisms. The aim is to document both treatment effects and potential harmful effects of ECT. Sample: n = 40 patients in a major depressive episode (bipolar and major depressive disorder). Two control groups with n = 15 in each group: age and gender matched healthy volunteers not receiving ECT and patients undergoing electrical cardioversion (ECV) for atrial fibrillation (AF). Observation time: six months. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04348825
Study type Observational
Source Haukeland University Hospital
Contact
Status Completed
Phase
Start date September 1, 2013
Completion date October 10, 2018
View Details
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